Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 14/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16651423 | 0.76 | BRD4 (0.47) | KDM4ESMN1; SMN2 | |
| SCHEMBL589113 | 0.76 | LMNA (0.35) | KDM4EALDH1A1PDE10A | |
| SCHEMBL3956392 | 0.75 | TNF (0.61) | KDM4EALDH1A1CYP2C19PDE10ASMN1; SMN2 | |
| SCHEMBL3169968 | 0.75 | CA12 (0.47) | KDM4EALDH1A1CYP2C19PDE10ASMN1; SMN2 | |
| SCHEMBL3161447 | 0.75 | KDM4E (0.41) | KDM4EALDH1A1CYP2C19PDE10ASMN1; SMN2 | |
| SCHEMBL20506971 | 0.74 | PDE10A (0.32) | KDM4EALDH1A1PDE10A | |
| SCHEMBL20704421 | 0.74 | GRIA1 (0.33) | KDM4EALDH1A1PDE10ASMN1; SMN2MAPK1 | |
| SCHEMBL19768920 | 0.73 | BRD4 (0.55) | KDM4EALDH1A1CYP2C19PDE10ASMN1; SMN2 | |
| SCHEMBL19785508 | 0.71 | ERN1 (0.35) | KDM4EALDH1A1CYP2C19 | |
| SCHEMBL16035792 | 0.71 | CNR1 (0.33) | KDM4EALDH1A1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1892241-A1 | NOVEL PIPERIDINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-02-27 | — | — | EP | disclosed |