SCHEMBL4941283

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4939682	0.85	ESR1 (0.48)	HSP90AA1ESR1ESR2TDP1TSHR
	SCHEMBL4939706	0.85	HSP90AA1 (0.41)	HSP90AA1ESR1CA12CA1CA2
	SCHEMBL4938798	0.81	MAOA (0.39)	HSP90AA1ESR1TDP1TSHRMAPK1
	SCHEMBL4943310	0.77	HSP90AA1 (0.64)	HSP90AA1ESR1ALDH1A1LMNAHPGD
	SCHEMBL4940434	0.76	ACHE (0.41)	HSP90AA1ESR1TDP1CA12CA1
	SCHEMBL4940666	0.76	MAPT (0.43)	ALDH1A1LMNAMAPTHPGDSMN1; SMN2
	SCHEMBL4936637	0.75	NPC1 (0.42)	HSP90AA1TDP1MAPK1LMNAKDM4E
	SCHEMBL4935271	0.73	KDM4E (0.50)	CA12CA1CA2CA7CA9
	SCHEMBL4933396	0.72	ESR1 (0.50)	HSP90AA1ESR1ESR2
	SCHEMBL4933212	0.72	ESR1 (0.50)	HSP90AA1ESR1APOBEC3GNOX4NOX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.