Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4941499 | 0.81 | CD274 (0.53) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Phenol SCHEMBL28331751 | 0.81 | PDCD1 (0.47) | PTPN5USP7CA2PLA2G2APTGER1 | |
| SCHEMBL7601609 | 0.80 | AKR1B1 (0.57) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL4235806 | 0.80 | AKR1B1 (0.47) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL4940053 | 0.78 | NR1H4 (0.46) | AKR1B1CA2CAMK2APTGER1PTGER4 | |
| SCHEMBL29101384 | 0.78 | AKR1B1 (0.48) | AKR1B1CYP2C9PTGS1PTGS2PLA2G2A | |
| SCHEMBL2392464 | 0.78 | PTGDR2 (0.50) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL2990732 | 0.77 | AKR1B1 (0.52) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| SCHEMBL559437 | 0.77 | AKR1B1 (0.62) | AKR1B1DUSP3PTPN5PTPN11CTDSP1 | |
| Bicarbonate SCHEMBL28365018 | 0.77 | FOLH1 (0.50) | CYP2C9S1PR1PLA2G2APTGER1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080004301-A1 | Benzene Compound Having 2 or More Substituents | NR1H2, NR1H3, NCOR2 | AKR1B1 588/4885DUSP3 4780/4885PTPN5 1414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.