Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.57 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.51 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CAMK2A | Q9UQM7 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961842 | 0.89 | PTGS1 (0.59) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL538512 | 0.88 | KMT2A (0.60) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL27701716 | 0.86 | KMT2A (0.58) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| Ammonia Solution, Strong SCHEMBL27926479 | 0.86 | KMT2A (0.58) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL8645744 | 0.86 | PTGS1 (0.55) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28594606 | 0.86 | KMT2A (0.58) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| Hydrochloric Acid SCHEMBL11895689 | 0.86 | KMT2A (0.58) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL29512995 | 0.86 | KMT2A (0.58) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL28408449 | 0.85 | PTGS1 (0.66) | AKR1B1PTGER1PTGER4PTGER3PTGER2 | |
| Ethane SCHEMBL28588588 | 0.85 | PTGS1 (0.57) | AKR1B1PTGER1PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017672-B1 | NEW NPY ANTAGONISTS | ASTRAZENECA AB (SE) | 2002-11-27 | — | — | EP | disclosed |
| US-6127414-A | NPY antagonists | ASTRA AKTIEBOLAG (SE) | 2000-10-03 | — | — | US | disclosed |
| EP-0302516-B1 | Optical article made of amorphous thermoplastic polyester resin | MITSUBISHI RAYON CO (JP) | 1993-12-15 | — | — | EP | disclosed |
| US-4910291-A | From aromatic diacid | MITSUBISHI RAYON COMPANY LTD. (JP) | 1990-03-20 | — | — | US | disclosed |
| EP-0302516-A2 | Optical article made of amorphous thermoplastic polyester resin | MITSUBISHI RAYON CO., LTD. (JP) | 1989-02-08 | — | — | EP | disclosed |