SCHEMBL4941508

SCHEMBL4941508

C[Si](C)(C)O[Si](C)(CCCNCCN)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.44
CA6 P23280 5/20 0.44
CA7 P43166 5/20 0.44
CA9 Q16790 5/20 0.44
CA14 Q9ULX7 5/20 0.44
CA5B Q9Y2D0 5/20 0.44
CA2 P00918 4/20 0.44
CA4 P22748 4/20 0.44
CA5A P35218 4/20 0.44
CA3 P07451 3/20 0.44
MEN1 O00255 2/20 0.42
RECQL P46063 2/20 0.42
KMT2A Q03164 2/20 0.42
LMNA P02545 3/20 0.40
TDP1 Q9NUW8 3/20 0.40
ALOX15 P16050 3/20 0.40
CA1 P00915 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
KDM4E B2RXH2 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10108305 0.93 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL15489979 0.91 CA12 (0.37) CA12CA6CA7CA9CA14
SCHEMBL5157938 0.90 CA12 (0.39) CA12CA6CA7CA9CA14
SCHEMBL13038582 0.90 CA12 (0.39) CA12CA6CA7CA9CA14
SCHEMBL12761070 0.89 CA12 (0.35) CA12CA6CA7CA9CA14
SCHEMBL19286519 0.89 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL16886920 0.88 CA12 (0.34) CA12CA6CA7CA9CA14
SCHEMBL16276115 0.87 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL15489990 0.87 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL20254149 0.85 CA12 (0.32) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10358541-B2 Organopolysiloxanes and methods for preparing same ELKEM SILICONES FRANCE SAS (FR) 2019-07-23 US disclosed
US-10358541-B2 Organopolysiloxanes and methods for preparing same ELKEM SILICONES FRANCE SAS (FR) 2019-07-23 US disclosed
US-20180265668-A1 ORGANOPOLYSILOXANES AND METHODS FOR PREPARING SAME ELKEM SILICONES FRANCE SAS (FR) 2018-09-20 US disclosed
US-9970740-B2 Viscous liquid monopropellant ROCKET LAB USA, INC. (US) 2018-05-15 US disclosed
US-20180125764-A1 KIT OF PARTS FOR CONDUCTING A DENTAL IMPRESSION AND RETRACTION PROCESS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2018-05-10 US disclosed
EP-3237070-A1 ORGANOPOLYSILOXANES AND METHODS FOR PREPARING SAME Bluestar Silicones France SAS (FR) 2017-11-01 EP disclosed
WO-2016102498-A1 ORGANOPOLYSILOXANES AND METHODS FOR PREPARING SAME BLUESTAR SILICONES FRANCE SAS (FR) 2016-06-30 WO disclosed
US-20120234196-A1 Viscous Liquid Monopropellant PLANETARY SYSTEMS CORPORATION 2012-09-20 US disclosed
US-7732508-B2 For making crowns, bridges, dentures and other oral prostheses; mixture of at least diunsaturated polysiloxane; an organohydrogensiloxane; alkylsiloxane having at least one carbinol, carboxy or amino group; condensation curing agent; and precious metal catalyst 3M ESPE AG (DE) 2010-06-08 US disclosed
US-20090275722-A1 AUTOMIXABLE PUTTY IMPRESSION MATERIAL 3M INNOVATIVE PROPERTIES COMPANY 2009-11-05 US disclosed
US-7572842-B2 Automixable putty impression material 3M ESPE AG 2009-08-11 US disclosed
US-20080075981-A1 Magnetic recording medium HITACHI MAXELL, LTD. (JP) 2008-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180125764-A1 KIT OF PARTS FOR CONDUCTING A DENTAL IMPRESSION AND RETRACTION PROCESS PHAX, SETDB1, CAD CA12 4175/4885CA6 3149/4885CA7 1855/4885
US-10358541-B2 Organopolysiloxanes and methods for preparing same IDUA, MAN2B1, ALG1 CA12 966/4885CA6 395/4885CA7 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.