SCHEMBL10108305

SCHEMBL10108305

C[Si](C)(C)O[Si](C)(C)O[Si](C)(CCCNCCN)O[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.38
CA6 P23280 5/20 0.38
CA7 P43166 5/20 0.38
CA9 Q16790 5/20 0.38
CA14 Q9ULX7 5/20 0.38
CA5B Q9Y2D0 5/20 0.38
CA2 P00918 4/20 0.38
CA4 P22748 4/20 0.38
CA5A P35218 4/20 0.38
CA3 P07451 3/20 0.38
MEN1 O00255 2/20 0.36
RECQL P46063 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 3/20 0.34
ALOX15 P16050 3/20 0.34
TDP1 Q9NUW8 2/20 0.34
CA1 P00915 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TP53 P04637 1/20 0.34
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13038582 0.98 CA12 (0.39) CA12CA6CA7CA9CA14
SCHEMBL19286519 0.96 CA12 (0.38) CA12CA6CA7CA9CA14
SCHEMBL4941508 0.93 CA12 (0.44) CA12CA6CA7CA9CA14
SCHEMBL20254149 0.92 CA12 (0.32) CA12CA6CA7CA9CA14
SCHEMBL15489990 0.90 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL16276115 0.90 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL18353431 0.90 CA12 (0.33) CA12CA6CA7CA9CA14
SCHEMBL20348758 0.90 CA12 (0.35) CA12CA6CA7CA9CA14
SCHEMBL13948929 0.90 CA12 (0.35) CA12CA6CA7CA9CA14
SCHEMBL12761070 0.90 CA12 (0.35) CA12CA6CA7CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357984-A1 ACTIVE AGENT-CONTAINING ARTICLES AND PRODUCT-SHIPPING ASSEMBLIES FOR CONTAINING THE SAME PROCTER & GAMBLE (US) 2023-11-09 US disclosed
US-11800917-B2 Hair-treatment compositions and methods of use L'OREAL (FR) 2023-10-31 US disclosed
US-20230295433-A1 SILICONE EMULSION COMPOSITION AND FIBER TREATMENT AGENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-09-21 US disclosed
US-20230270641-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR L'OREAL (FR) 2023-08-31 US disclosed
US-20230190625-A1 PROCESS FOR ALTERING THE COLOR OF KERATIN FIBERS L'OREAL (FR) 2023-06-22 US disclosed
US-20230159757-A1 DIRT-REPELLING CLEANING COMPOSITIONS AND METHODS OF USE THEREOF JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2023-05-25 US disclosed
US-20180161783-A1 FUNCTIONALIZED SILICONES FOR FROTH FLOTATION ECOLAB USA INC. 2018-06-14 US disclosed
US-20180117221-A1 COATING AGENT AND MEDICAL INSTRUMENT SURFACE TREATED WITH COATING AGENT TERUMO KABUSHIKI KAISHA (JP) 2018-05-03 US disclosed
US-20180117220-A1 COATING AGENT AND MEDICAL INSTRUMENT SURFACE TREATED WITH COATING AGENT TERUMO KABUSHIKI KAISHA (JP) 2018-05-03 US disclosed
US-9865490-B2 Cyclic olefin polymer compositions and polysiloxane release layers for use in temporary wafer bonding processes BREWER SCIENCE INC. (US) 2018-01-09 US disclosed
US-20070286837-A1 Hair care composition comprising an aminosilicone and a high viscosity silicone copolymer emulsion PROCTER & GAMBLE COMPANY, THE 2007-12-13 US disclosed
US-20070258936-A1 Composition for washing keratin materials and cosmetic treatment process using said composition L'OREAL S.A. (FR) 2007-11-08 US disclosed
US-20070185261-A1 Siloxane dispersant and nanoparticle paste composition comprising the same SAMSUNG ELECTRO-MACHANICS CO., LTD. (KR) 2007-08-09 US disclosed
US-7241853-B2 Printing processes employing intermediate transfer with molten intermediate transfer materials XEROX CORPORATION (US) 2007-07-10 US disclosed
US-20070128147-A1 Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network THE PROCTER & GAMBLE COMPANY 2007-06-07 US disclosed
US-20070110700-A1 Shampoo containing a gel network PROCTER & GAMBLE COMPANY, THE 2007-05-17 US disclosed
US-20070039103-A1 Fiber and hair fiber conditioning treatment composition THE PROCTER & GAMBLE COMPANY (US) 2007-02-22 US disclosed
US-7169745-B2 Hand dishwashing compositions comprising polymeric suds volume and suds duration enhancers and methods for washing with same THE PROCTER & GAMBLE CO. (US) 2007-01-30 US disclosed
US-20070020220-A1 A dipeptide with a C terminal threonine formulated for oral or topical administration or injection; cosmetics for hair, skin, and nails; improved aging resistance PROCTER & GAMBLE COMPANY, THE 2007-01-25 US disclosed
US-20070012895-A1 Highly concentrated, self-emulsifying preparations containing organopolysiloxanes and alkyl ammonium compounds and their use in aqueous systems RUDOLF GMBH & CO. KG CHEMISCHE FABRIK (DE) 2007-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270641-A1 COMPOSITIONS AND METHODS FOR TREATING HAIR UNG, OAT, OTC CA12 171/4885CA6 94/4885CA7 52/4885
US-20230190625-A1 PROCESS FOR ALTERING THE COLOR OF KERATIN FIBERS KRT18, VIM, PTMA CA12 141/4885CA6 30/4885CA7 20/4885
US-20070020220-A1 A dipeptide with a C terminal threonine formulated for oral or topical administration or injection; cosmetics for hair, skin, and nails; improved aging resistance KRT18, PRKDC, TTR CA12 4090/4885CA6 3151/4885CA7 3027/4885
US-20230357984-A1 ACTIVE AGENT-CONTAINING ARTICLES AND PRODUCT-SHIPPING ASSEMBLIES FOR CONTAINING THE SAME FSCN1, IDUA, PFAS CA12 1994/4885CA6 3146/4885CA7 2595/4885
US-20070286837-A1 Hair care composition comprising an aminosilicone and a high viscosity silicone copolymer emulsion SFN, CUTA, FAM83E CA12 3898/4885CA6 4338/4885CA7 1348/4885
US-11800917-B2 Hair-treatment compositions and methods of use CD44, CUTA, TYR CA12 662/4885CA6 2223/4885CA7 1654/4885
US-20070258936-A1 Composition for washing keratin materials and cosmetic treatment process using said composition KRT18, DSG1, CUTA CA12 1457/4885CA6 3470/4885CA7 1736/4885
US-20070128147-A1 Composition comprising a particulate zinc material, a pyrithione or a polyvalent metal salt of a pyrithione and a gel network PAOX, SCO2, SFN CA12 3350/4885CA6 4217/4885CA7 3140/4885
US-20070110700-A1 Shampoo containing a gel network POLR1C, POLQ, POLN CA12 4670/4885CA6 4565/4885CA7 3844/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.