Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19567138 | 0.92 | ACE (0.63) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL15706369 | 0.92 | ACE (0.63) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL19567159 | 0.88 | ACE (0.58) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL30291800 | 0.87 | ACE (0.60) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL30887591 | 0.87 | ACE (0.60) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL19051497 | 0.87 | HDAC1 (0.67) | POLBHDAC1HDAC6 | |
| SCHEMBL19567162 | 0.86 | ACE (0.59) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL8675408 | 0.86 | HDAC1 (0.57) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL10076050 | 0.84 | MAPT (0.58) | ACEPOLBMAPTKLK5TDP1 | |
| SCHEMBL19567163 | 0.84 | MAPT (0.58) | ACEPOLBMAPTKLK5TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
| US-20070259889-A1 | Protein Binding Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2007-11-08 | — | — | US | disclosed |
| US-20070259889-A1 | Protein Binding Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2007-11-08 | — | — | US | disclosed |
| US-20070259889-A1 | Protein Binding Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2007-11-08 | — | — | US | disclosed |
| EP-1804838-A2 | DRUG CONJUGATES OF LONG CHAIN FATTY ACID OR ESTER MOIETIES AS PROTEIN BINDING PRODRUGS | Drug Discovery Laboratory AS (NO) | 2007-07-11 | — | — | EP | disclosed |
| EP-1663181-A2 | PROTEIN BINDING COMPOUNDS | Drug Discovery Laboratory AS (NO) | 2006-06-07 | — | — | EP | disclosed |
| WO-2006030217-A2 | DRUG CONJUGATES OF LONG CHAIN FATTY ACID OR ESTER MOIETIES AS PROTEIN BINDING PRODRUGS | DRUG DISCOVERY LABORATORY AS (NO) | 2006-03-23 | — | — | WO | disclosed |
| WO-2005025552-A2 | PROTEIN BINDING COMPOUNDS | DRUG DISCOVERY LABORATORY AS (NO) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259889-A1 | Protein Binding Compounds | FABP1, FABP3, FABP2 | ACE 427/4885POLB 3589/4885MAPT 1968/4885 |
| US-20080103110-A1 | Compounds | ATIC, CDA, PAICS | ACE 3255/4885POLB 693/4885MAPT 4869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.