Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 7/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.51 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9575948 | 0.86 | HDAC1 (0.60) | HDAC1HDAC6POLBHDAC3HDAC4 | |
| SCHEMBL4941724 | 0.86 | ACE (0.58) | HDAC1HDAC6ACEKLK5POLB | |
| SCHEMBL8467166 | 0.86 | FAAH (0.62) | HDAC1HDAC6ACEHDAC3HDAC4 | |
| SCHEMBL9218164 | 0.86 | FAAH (0.62) | HDAC1HDAC6ACEHDAC3HDAC4 | |
| SCHEMBL8466442 | 0.86 | FAAH (0.62) | HDAC1HDAC6ACEHDAC3HDAC4 | |
| SCHEMBL30291800 | 0.83 | ACE (0.60) | ACEKLK5POLBMAPTTDP1 | |
| SCHEMBL15706369 | 0.83 | ACE (0.63) | ACEKLK5POLBMAPTTDP1 | |
| SCHEMBL19567138 | 0.83 | ACE (0.63) | ACEKLK5POLBMAPTTDP1 | |
| SCHEMBL30887591 | 0.83 | ACE (0.60) | ACEKLK5POLBMAPTTDP1 | |
| SCHEMBL19567162 | 0.82 | ACE (0.59) | ACEKLK5POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5744631-A | Fatty acid analogs and prodrugs | G.D. SEARLE & CO. (US) | 1998-04-28 | — | — | US | disclosed |