Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Benzoquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA known ✓ | P21397 | 1/20 | 0.61 |
| ▸ | MAOB known ✓ | P27338 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | BLM | P54132 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | RECQL | P46063 | 3/20 | 0.61 |
| ▸ | CASP1 | P29466 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | BCHE | P06276 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.61 |
| ▸ | DHODH | Q02127 | 1/20 | 0.61 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.61 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoquinone SCHEMBL3238193 | 1.00 | TDP1 (0.61) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL27939443 | 1.00 | TDP1 (0.61) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL27730092 | 1.00 | TDP1 (0.61) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL27878726 | 0.96 | TDP1 (0.57) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL28528775 | 0.96 | TDP1 (0.57) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL27390105 | 0.96 | TDP1 (0.57) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL8035204 | 0.86 | TDP1 (0.53) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL27655062 | 0.86 | ALDH1A1 (0.53) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL10959883 | 0.86 | TDP1 (0.53) | TDP1BLMALDH1A1RECQLCASP1 | |
| Benzoquinone SCHEMBL11308712 | 0.85 | HPGD (0.54) | TDP1BLMALDH1A1RECQLCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104540396-A | Taste-masking compositions, sweetener compositions and consumable product compositions containing the same | NUTRINOVA GMBH | 2015-04-22 | — | — | CN | claimed |
| CN-87201300-U | POLARISED LIGHT ANTIDAZZLE LIGHTING | — | 1988-03-09 | — | — | CN | claimed |
| CN-114423290-B | Melanoidin compositions for protecting crops from nonfungal pests | 以色列国家农业和农村发展农业研究组织沃尔坎尼中心 | 2024-04-09 | — | — | CN | disclosed |
| CN-106978160-B | Nitrogen sulfur doping carbon namo fluorescence probe environment-friendly preparation method thereof | 大连工业大学 | 2019-07-05 | — | — | CN | disclosed |
| CN-109777849-A | A kind of de- bitter peach kernel extracts the preparation method of proteolysis polypeptide | 中南林业科技大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-107847398-B | Control the pharmaceutical dosage form of release | 南京三迭纪医药科技有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-106147760-B | A kind of preparation method of transient metal doped carbon fluorescence quantum | 中国科学院大连化学物理研究所 | 2019-03-05 | — | — | CN | disclosed |
| CN-109328020-A | Composition and method for small-sized canid | 雀巢产品技术援助有限公司 | 2019-02-12 | — | — | CN | disclosed |
| CN-109097034-A | It is a kind of using cotton stalk skins as the preparation method of carbon source La doped carbon quantum dot composite material | 济南大学 | 2018-12-28 | — | — | CN | disclosed |
| CN-109054829-A | A kind of palm bark is the preparation method of carbon source praseodymium doped carbon quantum dot composite material | 济南大学 | 2018-12-21 | — | — | CN | disclosed |
| CN-109021969-A | It is a kind of using cotton as the preparation method of carbon source samarium doping carbon quantum dot composite material | 济南大学 | 2018-12-18 | — | — | CN | disclosed |
| US-20070031717-A1 | Composite proton exchange membrane and method of manufacturing the same | GINER ELX SUB, INC. | 2007-02-08 | — | — | US | disclosed |
| US-7135132-B2 | Photochromic fluorescent polymer and preparation method thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-11-14 | — | — | US | disclosed |
| US-20040115498-A1 | Composite proton exchange membrane and method of manufacturing the same | GINER ELX SUB, INC. | 2004-06-17 | — | — | US | disclosed |
| WO-2004042845-A2 | COMPOSITE PROTON EXCHANGE MEMBRANE AND METHOD OF MANUFACTURING THE SAME | GINER ELECTROCHEMICAL SYSTEMS, LLC (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20030213942-A1 | Photochromic fluorescent polymer and preparation method thereof | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY | 2003-11-20 | — | — | US | disclosed |
| CN-1348377-A | Method for the treatment of severe chronic bronchitis (bronchiectasis) with an aerosolized antibiotic | PATHOGENESIS CORP (US) | 2002-05-08 | — | — | CN | disclosed |
| CN-87201300-U | POLARISED LIGHT ANTIDAZZLE LIGHTING | — | 1988-03-09 | — | — | CN | disclosed |
| US-4385108-A | SILVER HALIDE EMULSION FILM HAVING A LAYER CONTAINING A HYDROQUINONE DEVELOPER AND A HYDRAZIDE; STABILITY; OFFSET PRINTING | FUJI PHOTO FILM CO., LTD. (JP) | 1983-05-24 | — | — | US | disclosed |
| US-4313967-A | Intermediate-moisture frozen foods | RICH PRODUCTS CORPORATION (US) | 1982-02-02 | — | — | US | disclosed |