Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057477 | 0.81 | SMN1; SMN2 (0.39) | SMN1; SMN2GAAALDH1A1KDM4EOPRL1 | |
| SCHEMBL4057100 | 0.79 | GRIN2D (0.37) | SMN1; SMN2ALDH1A1KDM4EOPRL1RECQL | |
| SCHEMBL4065508 | 0.77 | RECQL (0.40) | SMN1; SMN2GAAALDH1A1KDM4EOPRL1 | |
| SCHEMBL4059578 | 0.76 | NPSR1 (0.37) | ALDH1A1OPRL1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL4054128 | 0.76 | OPRL1 (0.34) | SMN1; SMN2KDM4EOPRL1RECQL | |
| SCHEMBL3596885 | 0.74 | PTPN1 (0.41) | KDM4EOPRL1RECQL | |
| SCHEMBL4942982 | 0.72 | HTT (0.41) | OPRL1CYP3A4EP300KAT2BHTT | |
| SCHEMBL3600126 | 0.71 | MGLL (0.39) | SMN1; SMN2ALDH1A1KDM4EOPRL1HPGD | |
| SCHEMBL3604966 | 0.71 | MEN1 (0.39) | ALDH1A1KDM4EOPRL1HSD17B10HPGD | |
| SCHEMBL3598970 | 0.71 | MGLL (0.39) | SMN1; SMN2ALDH1A1KDM4EOPRL1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080161366-A1 | AMINOALKYL SUBSTITUTED ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | SLC6A4, SLC6A2, SLC6A3 | SMN1; SMN2 356/4885PLD1 4313/4885GAA 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.