Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509376 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL329237 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL5144146 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL339719 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL2871187 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL338315 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL5495328 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL659359 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL4441590 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL1664155 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040067991-A1 | Tetrahydrobenzothiazole analogues as neuroprotective agents | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE | 2004-04-08 | — | — | US | claimed |
| EP-1303502-A2 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-23 | — | — | EP | claimed |
| WO-2002004409-A2 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS | US GOV HEALTH & HUMAN SERV (US) | 2002-01-17 | — | — | WO | claimed |
| US-5681689-A | COUPLING WITH OXIDIZED COLOR DEVELOPER | EASTMAN KODAK COMPANY (US) | 1997-10-28 | — | — | US | claimed |
| US-5354642-A | Polymeric couplers for heat image separation systems | EASTMAN KODAK COMPANY (US) | 1994-10-11 | — | — | US | claimed |
| US-4690889-A | SUBSTITUTED NAPHTHOL, HEAT AND LIGHT FASTNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-01 | — | — | US | claimed |
| US-20080319032-A1 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS | GREIG NIGEL H | 2008-12-25 | — | — | US | disclosed |
| US-20040067991-A1 | Tetrahydrobenzothiazole analogues as neuroprotective agents | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES, THE | 2004-04-08 | — | — | US | disclosed |
| EP-1303502-A2 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-0745894-B1 | Black and white photographic elements containing release compounds and method of preparing photographic emulsion | EASTMAN KODAK CO (US) | 2003-01-22 | — | — | EP | disclosed |
| WO-2002004409-A2 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS | US GOV HEALTH & HUMAN SERV (US) | 2002-01-17 | — | — | WO | disclosed |
| US-6265118-B1 | THIADIAZOLE DYTES; LIGHTFASTNESS; DIFFUSION DYE TRANSFER | FUJI PHOTO FILM CO., LTD. (JP) | 2001-07-24 | — | — | US | disclosed |
| EP-0813112-B1 | Photographic elements containing new magenta dye-forming couplers | EASTMAN KODAK CO (US) | 2000-12-13 | — | — | EP | disclosed |
| US-4690889-A | SUBSTITUTED NAPHTHOL, HEAT AND LIGHT FASTNESS | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| EP-0161626-A2 | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1985-11-21 | — | — | EP | disclosed |
| EP-0114675-A2 | Color photographic silver halide light-sensitive material | FUJI PHOTO FILM CO., LTD. (JP) | 1984-08-01 | — | — | EP | disclosed |
| US-4200466-A | Light-sensitive silver halide photographic materials | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-04-29 | — | — | US | disclosed |
| US-4195996-A | FLUORESCENT INTENSIFYING SCREEN, QUINONE-IMINE DYE FORMERS | FUJI PHOTO FILM CO., LTD. (JP) | 1980-04-01 | — | — | US | disclosed |
| US-4183752-A | DEVELOPMENT INHIBITOR RELEASING THIOETHERS | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1980-01-15 | — | — | US | disclosed |
| US-4052213-A | OXAZOLINONE-2-COMPOUNDS CONTAINING A MERCAPTO GROUP | AGFA-GEVAERT, A.G. (DT) | 1977-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040067991-A1 | Tetrahydrobenzothiazole analogues as neuroprotective agents | BAX, BAD, BCL2 | LTA4H 1066/4885TSHR 2877/4885LMNA 1580/4885 |
| US-20080319032-A1 | TETRAHYDROBENZOTHIAZOLE ANALOGUES AS NEUROPROTECTIVE AGENTS | BAX, BAD, BCL2 | LTA4H 1066/4885TSHR 2877/4885LMNA 1580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.