Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1509376 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL5144146 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL339719 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL2871187 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL338315 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL5495328 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL659359 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL4441590 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL4943659 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 | |
| SCHEMBL1664155 | 1.00 | LTA4H (0.44) | LTA4HTSHRLMNAALDH1A1NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106232120-B | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2- (1H) -ones | 爱尔皮奥治疗有限公司 | 2021-01-08 | — | — | CN | claimed |
| CN-108383980-B | Thermally induced delayed fluorescence polymer with main chain containing diphenyl silicon and carbazole units and preparation method thereof | 中国科学院长春应用化学研究所 | 2020-07-07 | — | — | CN | claimed |
| CN-108383980-A | A kind of thermal induction delayed fluorescence polymer and preparation method thereof of main chain silicon containing diphenyl and carbazole unit | 中国科学院长春应用化学研究所 | 2018-08-10 | — | — | CN | claimed |
| CN-107151264-A | Antimicrobial-oritavancin derivative and pharmaceutical composition, with and its production and use | 浙江医药股份有限公司新昌制药厂 | 2017-09-12 | — | — | CN | claimed |
| EP-3107542-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | Aerpio Therapeutics, Inc. (US) | 2016-12-28 | — | — | EP | claimed |
| US-9388135-B2 | Process for preparing N-benzyl-3-hydroxy-4-substituted-pyridin-2-(1H)-ones | AERPIO THERAPEUTICS, INC. (US) | 2016-07-12 | — | — | US | claimed |
| CN-103145730-B | Two thieno-fluorenes and derivative and preparation method | EAST CHINA NORMAL UNIVERSITY (CN) | 2016-02-03 | — | — | CN | claimed |
| WO-2015126860-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. (US) | 2015-08-27 | — | — | WO | claimed |
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | AERPIO THERAPEUTICS, INC. | 2015-08-20 | — | — | US | claimed |
| US-8835498-B2 | Anti-wrinkle agents | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-16 | — | — | US | claimed |
| EP-0766665-B1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARM (GB) | 1999-07-28 | — | — | EP | claimed |
| WO-1999004789-A1 | SUBSTITUTED AURONE DERIVATIVES | PHYTERA, INC. (US) | 1999-02-04 | — | — | WO | claimed |
| CN-1036715-C | Cyclic peptide antifungal agents and process for preparation thereof | LILLY CO ELI (US) | 1997-12-17 | — | — | CN | claimed |
| CN-1151157-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARM (GB) | 1997-06-04 | — | — | CN | claimed |
| EP-0766665-A2 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1997-04-09 | — | — | EP | claimed |
| WO-1995035276-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-12-28 | — | — | WO | claimed |
| CN-1080926-A | Cyclic peptide antifungal agents and preparation method thereof | LILLY CO ELI (US) | 1994-01-19 | — | — | CN | claimed |
| CN-1038279-A | PYRAZOLOPYRIDINE TYPE MEVALONOLACTONES | NISSAN CHEMICAL IND LTD (JP) | 1989-12-27 | — | — | CN | claimed |
| US-4629798-A | FROM VINYLENE ESTEPS, KETONES, OR NITRILES AND TOSYLMETHYLISOCYANIDE | THE B. F. GOODRICH COMPANY (US) | 1986-12-16 | — | — | US | claimed |
| US-4604471-A | PLASTIC STABILIZERS | BASF AKTIENGESELLSCHAFT (DE) | 1986-08-05 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232425-A1 | PROCESS FOR PREPARING N-BENZYL-3-HYDROXY-4-SUBSTITUTED-PYRIDIN-2-(1H)-ONES | CYP4B1, CYP8B1, HPD | LTA4H 1336/4885TSHR 3422/4885LMNA 954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.