Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355896 | 0.84 | ALDH1A1 (0.49) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL11694927 | 0.80 | POLB (0.68) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL4945318 | 0.80 | POLB (0.53) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL9787811 | 0.79 | POLB (0.65) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL11694716 | 0.79 | POLB (0.65) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL11208031 | 0.78 | POLB (0.47) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL4935870 | 0.77 | POLB (0.46) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL11677768 | 0.76 | POLB (0.74) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 | |
| SCHEMBL11162436 | 0.76 | HTR1A (0.37) | SMN1; SMN2PLA2G7RAB9A | |
| SCHEMBL5584328 | 0.75 | POLB (0.61) | POLBSMN1; SMN2ALDH1A1PADI4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1530576-B1 | HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS | UNIV AUBURN (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20080003438-A1 | Heterocyclic siloxanes for use in biocidal coatings and materials | AUBURN UNIVERSITY (US) | 2008-01-03 | — | — | US | disclosed |
| US-6969769-B2 | N-halamine siloxanes for use in biocidal coatings and materials | VANSON HALOSOURCE, INC. (US) | 2005-11-29 | — | — | US | disclosed |
| EP-1530576-A2 | HETEROCYCLIC HALAMINE-SUBSTITUTED SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS | Auburn University (US) | 2005-05-18 | — | — | EP | disclosed |
| US-20040127667-A1 | N-halamine siloxanes for use in biocidal coatings and materials | AUBURN UNIVERSITY | 2004-07-01 | — | — | US | disclosed |
| WO-2003106466-A2 | N-HALAMINE SILOXANES FOR USE IN BIOCIDAL COATINGS AND MATERIALS | AUBURN UNIVERSITY (US) | 2003-12-24 | — | — | WO | disclosed |