SCHEMBL4944143

SCHEMBL4944143

C=C(C(=O)O)C(C)NC(F)CCC

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 1/20 0.33
AKR1A1 P14550 1/20 0.33
CHRM3 P20309 1/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ADRA1A P35348 1/20 0.33
HRH1 P35367 1/20 0.33
DRD3 P35462 1/20 0.33
SLC6A3 Q01959 1/20 0.33
HDAC1 Q13547 1/20 0.33
HDAC2 Q92769 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.32
HDAC7 Q8WUI4 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
HDAC9 Q9UKV0 1/20 0.31
HDAC5 Q9UQL6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4746531 0.81 CHRM1 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL4741788 0.72 MAPT (0.42) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL7894760 0.72 TDP1 (0.33) TDP1MAPT
SCHEMBL3261388 0.70 CHRM1 (0.42) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL5220921 0.69 CYP2D6 (0.30)
SCHEMBL5015870 0.68 ALDH1A1 (0.39)
SCHEMBL3820321 0.68 HDAC1 (0.56) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL1259560 0.68 HDAC1 (0.44) CHRM1AKR1A1CHRM3HTR2AHTR2C
Oxalic Acid SCHEMBL1420324 0.67 ALOX15 (0.43) CHRM1AKR1A1CHRM3HTR2AHTR2C
SCHEMBL21436498 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945229-A2 METHODS FOR FABRICATION OF ANTIMICROBIAL SURFACES Research Foundation of the City University of New York (US) 2008-07-23 EP disclosed
WO-2008018890-A2 METHODS FOR FABRICATION OF ANTIMICROBIAL SURFACES RESEARCH FOUNDATION OF CITY UNIVERSITY OF NEW YORK (US) 2008-02-14 WO disclosed