Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 2/20 | 0.43 |
| ▸ | SMARCA4 | P51532 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943483 | 0.93 | SMARCA2 (0.43) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL4947805 | 0.91 | SMARCA2 (0.51) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL14339633 | 0.89 | SMARCA2 (0.44) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL4944907 | 0.86 | IKBKB (0.57) | IKBKB | |
| SCHEMBL4947201 | 0.84 | SMARCA2 (0.51) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL4938233 | 0.84 | SMARCA2 (0.51) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL4947972 | 0.84 | SMARCA2 (0.51) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL4945530 | 0.83 | IKBKB (0.49) | FEN1ALOX5APIKBKB | |
| SCHEMBL5425664 | 0.82 | SMARCA2 (0.44) | SMARCA2SMARCA4PBRM1USP30FEN1 | |
| SCHEMBL14046508 | 0.81 | SMARCA2 (0.54) | SMARCA2SMARCA4PBRM1USP30FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7435743-B2 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2008-10-14 | — | — | US | disclosed |
| US-20060205676-A1 | Pyridine derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205676-A1 | Pyridine derivatives | CBR3, ARG1, HRH3 | SMARCA2 2927/4885SMARCA4 2634/4885PBRM1 2248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.