Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | GSR | P00390 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | HTR2B | P41595 | 2/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12192916 | 0.80 | GABRA1 (0.50) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL18262866 | 0.80 | GABRA1 (0.46) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL12869000 | 0.78 | GABRA1 (0.52) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL2788418 | 0.76 | THRA (0.47) | GABRA1GABRB1CA1CA2GABRB2 | |
| Tribromometacresol SCHEMBL30255705 | 0.75 | CA1 (0.52) | GABRA1GABRB1CA1CA2GABRB2 | |
| Tribromometacresol SCHEMBL467297 | 0.75 | CA1 (0.52) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL18272114 | 0.74 | GABRA1 (0.44) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL19003619 | 0.73 | PTPN1 (0.44) | CA1CA2LMNACYP1A2CYP3A4 | |
| SCHEMBL2051242 | 0.73 | CA1 (0.42) | GABRA1GABRB1CA1CA2GABRB2 | |
| SCHEMBL5587079 | 0.72 | GABRA1 (0.56) | GABRA1GABRB1CA1CA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070056901-A1 | Solvent-resistant membranes from solvent-inert polyimides and polyketones | GENERAL ELECTRIC COMPANY | 2007-03-15 | — | — | US | claimed |
| US-7439291-B2 | Solvent-resistant membranes from solvent-inert polyimides and polyketones | GENERAL ELECTRIC COMPANY (US) | 2008-10-21 | — | — | US | disclosed |
| US-20070056901-A1 | Solvent-resistant membranes from solvent-inert polyimides and polyketones | GENERAL ELECTRIC COMPANY | 2007-03-15 | — | — | US | disclosed |
| US-20070060688-A1 | Solvent-resistant membranes from solvent-inert polyimides and polyketones | GENERAL ELECTRIC COMPANY | 2007-03-15 | — | — | US | disclosed |