Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.48 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948623 | 0.86 | CYP19A1 (0.44) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL3356889 | 0.85 | CYP19A1 (0.44) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL6301569 | 0.85 | CYP19A1 (0.44) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL9947828 | 0.83 | CYP19A1 (0.42) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL8370954 | 0.82 | CYP19A1 (0.41) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL9948721 | 0.82 | CYP19A1 (0.41) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL6244893 | 0.82 | SERPINA6 (0.41) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL6832273 | 0.81 | CYP19A1 (0.65) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL3816344 | 0.81 | SERPINA6 (0.72) | SHBGSERPINA6ALDH1A1SLC22A1THRB | |
| SCHEMBL6244949 | 0.81 | AR (0.49) | SHBGCYP19A1GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113677348-A | Treatment of migraine | 费林药业公司 | 2021-11-19 | — | — | CN | claimed |
| CN-107206010-B | C-19 steroids to inhibit neovascularization | 库拉迪斯有限公司 | 2021-12-21 | — | — | CN | disclosed |
| CN-113677348-A | Treatment of migraine | 费林药业公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-113677348-A | Treatment of migraine | 费林药业公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-113117089-A | C-19 steroids to inhibit neovascularization | 库拉迪斯有限公司 | 2021-07-16 | — | — | CN | disclosed |
| WO-2020061584-A1 | TASTE-MASKED DOSAGE FORMS | MSB HOLDINGS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| US-20080075772-A1 | PHARMACEUTICAL COMPOSITIONS HAVING NOVEL SCORING PATTERNS AND METHODS OF USING THOSE COMPOSITIONS | ACCU-BREAK TECHNOLOGIES, INC. | 2008-03-27 | — | — | US | disclosed |
| EP-1379253-A1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA,11BETA-DIMETHYL-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2004-01-14 | — | — | EP | disclosed |
| WO-2003045398-A1 | METHODS OF MAKING AND PHARMACEUTICAL FORMULATIONS COMPRISING 7ALPHA, 11BETA-DIMETHY-17BETA-HYDROXYESTRA-4, 14-DIEN-3-ONE AND 17 ESTERS THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2003-06-05 | — | — | WO | disclosed |
| EP-0113812-B1 | PROCESS FOR THE PREPARATION OF 17-ALPHA-BROMOETHYNYL AND 17-ALPHA-IODOETHYNYL-17-BETA-HYDROXY STEROIDS, AND 17-ALPHA-BROMOETHYNYL AND 17-ALPHA-IODOETHYNYL-17-BETA-HYDROXY STEROIDS | SCHERING AKTIENGESELLSCHAFT (DE) | 1988-10-26 | — | — | EP | disclosed |