Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.44 |
| ▸ | SHBG | P04278 | 2/20 | 0.40 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9948623 | 0.86 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL4945163 | 0.85 | SHBG (0.48) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL6301569 | 0.85 | CYP19A1 (0.44) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9947828 | 0.83 | CYP19A1 (0.42) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL8370954 | 0.82 | CYP19A1 (0.41) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL9948721 | 0.82 | CYP19A1 (0.41) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL6244893 | 0.82 | SERPINA6 (0.41) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL10449145 | 0.80 | CYP19A1 (0.39) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL11977689 | 0.80 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 | |
| SCHEMBL922877 | 0.80 | CYP19A1 (0.66) | CYP19A1SHBGSERPINA6ALDH1A1SLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170925-B1 | 17ß -CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, USE THEREOF AND MEDICAMENTS CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |
| US-8207150-B2 | 17β-cyano-19-nor-androst-4-ene derivative, its use and medicaments comprising the derivative | Bayer Pharma AG (DE) | 2012-06-26 | — | — | US | disclosed |
| WO-2010066355-A1 | USE OF 17β-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVES FOR MANUFACTURING A MEDICAMENT IN A SUSTAINED-RELEASE FORM FOR PARENTERAL USE, AND SUSTAINED-RELEASE MEDICAMENT CONTAINING 17β-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVES FOR PARENTERAL USE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-06-17 | — | — | WO | disclosed |
| EP-2170925-A2 | 17ß -CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, USE THEREOF AND MEDICAMENTS CONTAINING SAID DERIVATIVE | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008151746-A2 | 17β-CYANO-19-NOR-ANDROST-4-ENE DERIVATIVE, USE THEREOF AND MEDICAMENTS CONTAINING SAID DERIVATIVE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |