SCHEMBL4945274

SCHEMBL4945274

COCCC(OC)=C(C)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
ALDH1A1 P00352 6/20 0.43
KDM4E B2RXH2 6/20 0.37
LMNA P02545 4/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
HPGD P15428 1/20 0.36
RECQL P46063 1/20 0.35
POLB P06746 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
APEX1 P27695 1/20 0.33
GAA P10253 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11118994 0.82 ALDH1A1 (0.41) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL11118996 0.82 ALDH1A1 (0.41) TSHRALDH1A1KDM4EMEN1KMT2A
SCHEMBL5712786 0.80 FNTA (0.41) TSHRALDH1A1GAA
SCHEMBL456878 0.80 FNTA (0.41) TSHRALDH1A1GAA
SCHEMBL429664 0.77 FNTA (0.47) TSHRALDH1A1MEN1KMT2ATDP1
SCHEMBL11341500 0.77 CAMK2A (0.41) TSHRALDH1A1GAA
SCHEMBL7021802 0.77 FNTA (0.47) TSHRALDH1A1MEN1KMT2ATDP1
SCHEMBL9058105 0.75 ALDH1A1 (0.36) TSHRALDH1A1LMNATDP1GAA
SCHEMBL460811 0.75 ALDH1A1 (0.36) TSHRALDH1A1LMNATDP1GAA
SCHEMBL28777952 0.73 TSHR (0.35) TSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2852631-B1 METHOD FOR PRODUCING A NANOCOMPOSITE DISPERSION COMPRISING COMPOSITE PARTICLES OF INORGANIC NANOPARTICLES AND ORGANIC POLYMERS AKZO NOBEL COATINGS INT BV (NL) 2019-11-20 EP claimed
EP-3790935-B1 A METHOD FOR PROVIDING COATING SYSTEMS WITH CORROSION-PROTECTIVE PROPERTIES THE UNIV OF THE BASQUE COUNTRY / INSTITUTE FOR POLYMER MATERIALS POLYMAT (ES) 2022-04-06 EP disclosed
US-7419619-B2 Mixtures for producing transparent plastics, transparent plastics and method for their production and use ROEHM GMBH & CO. KG (DE) 2008-09-02 US disclosed
US-20070135560-A1 Mixtures for producing transparent plastics, transparent plastics and method for their production and use ROEHM GBMH & CO. KG (DE) 2007-06-14 US disclosed