SCHEMBL28777952

SCHEMBL28777952

CO/C(CCl)=C(/C)C(=O)O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1066504 1.00 TSHR (0.35) TSHRALDH1A1MGAMGAASI
SCHEMBL460811 0.83 ALDH1A1 (0.36) TSHRALDH1A1MGAMGAASI
SCHEMBL9058105 0.83 ALDH1A1 (0.36) TSHRALDH1A1MGAMGAASI
SCHEMBL10949202 0.76 TRPA1 (0.39) TSHRALDH1A1MGAMGAASI
SCHEMBL8970474 0.76 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL5712786 0.74 FNTA (0.41) TSHRALDH1A1MGAMGAASI
SCHEMBL456878 0.74 FNTA (0.41) TSHRALDH1A1MGAMGAASI
SCHEMBL10602554 0.74 ALDH1A1 (0.39) ALDH1A1MGAMGAASIMGAM2
SCHEMBL4945274 0.73 TSHR (0.44) TSHRALDH1A1GAA
SCHEMBL27504478 0.72 ALDH1A1 (0.40) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685274-A Esterification method for preparing 4-methyl chloroacetoacetate 江西迪赛诺制药有限公司 2022-07-01 CN claimed
CN-114685274-A Esterification method for preparing 4-methyl chloroacetoacetate 江西迪赛诺制药有限公司 2022-07-01 CN disclosed
CN-114685274-A Esterification method for preparing 4-methyl chloroacetoacetate 江西迪赛诺制药有限公司 2022-07-01 CN disclosed