Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 9/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353291 | 1.00 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL9665042 | 1.00 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL4945588 | 1.00 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL27996293 | 0.85 | AOC3 (0.58) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL3266869 | 0.83 | UGT2B7 (0.61) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL2894556 | 0.82 | CYP2D6 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL6543395 | 0.82 | CYP2D6 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL6490271 | 0.82 | CYP2D6 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL10120474 | 0.80 | UGT2B7 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 | |
| SCHEMBL483715 | 0.80 | UGT2B7 (0.62) | SLC6A2SLC6A4SLC6A3CYP2D6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110982800-B | Sulfonyl transferase, application and mediated aziridine ring biosynthesis method thereof | 天津科技大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-109734643-B | Method for synthesizing pyrroline compound by catalyzing amino alcohol and enol with iron | 陕西师范大学 | 2021-05-14 | — | — | CN | disclosed |
| CN-110982800-A | Sulfonyl transferase, application and aziridine ring biological synthesis method mediated by sulfonyl transferase | 天津科技大学 | 2020-04-10 | — | — | CN | disclosed |
| CN-109734643-A | The method that iron catalytic amino alcohol synthesizes pyrrolines with enol | 陕西师范大学 | 2019-05-10 | — | — | CN | disclosed |
| WO-2012168733-A1 | SUBSTITUTED 8 - AMINO - IMIDAZO [1, 2-A] PYRAZINES AS ANTIBACTERIAL AGENTS | UCL BUSINESS PLC (GB) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012168733-A1 | SUBSTITUTED 8 - AMINO - IMIDAZO [1, 2-A] PYRAZINES AS ANTIBACTERIAL AGENTS | UCL BUSINESS PLC (GB) | 2012-12-13 | — | — | WO | disclosed |
| US-20080167318-A1 | Pharmaceutically active pyrrolidine derivatives | APPLIED RESEARCH SYSTEM ARS HOLDING N.V. (NL) | 2008-07-10 | — | — | US | disclosed |
| US-7211601-B2 | Pharmaceutically active pyrrolidine derivatives | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-05-01 | — | — | US | disclosed |
| CN-1296354-C | Pharmaceutically active pyrrolidine derivatives | APPLIED RES SYSTEMS AKS HOLDIN (AN) | 2007-01-24 | — | — | CN | disclosed |
| EP-1268419-B1 | PYRROLIDINE DERIVATIVES USEFUL AS BAX INHIBITORS | APPLIED RESEARCH SYSTEMS (AN) | 2006-06-21 | — | — | EP | disclosed |
| EP-0590793-A1 | Oxazolidine derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | SANKYO COMPANY LIMITED (JP) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993024470-A1 | ARTHROPODICIDAL OXAZOLINES AND THIAZOLINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| EP-0365045-B1 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-12-01 | — | — | EP | disclosed |
| CN-1073428-A | Aromatic amino alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-06-23 | — | — | CN | disclosed |
| EP-0543662-A2 | Aromatic amino-alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic uses | Sankyo Company Limited (JP) | 1993-05-26 | — | — | EP | disclosed |
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0365045-A1 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1990-04-25 | — | — | EP | disclosed |
| US-4699905-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1987-10-13 | — | — | US | disclosed |
| EP-0161801-A2 | Perhydrothiazepine derivatives, their preparation and their therapeutic use | SANKYO COMPANY LIMITED (JP) | 1985-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080167318-A1 | Pharmaceutically active pyrrolidine derivatives | OXTR, PRLHR, NR0B1 | SLC6A2 3842/4885SLC6A4 3520/4885SLC6A3 3366/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.