SCHEMBL2894556

SCHEMBL2894556

OCC(O)c1ccc2ccccc2c1

nearest known ligand 0.59

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 5/20 0.59
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
AOC3 Q16853 1/20 0.59
CYP1A2 P05177 1/20 0.59
TSHR P16473 1/20 0.59
HIF1A Q16665 1/20 0.59
UGT2B7 P16662 1/20 0.59
SLC6A2 P23975 12/20 0.50
SLC6A4 P31645 12/20 0.50
SLC6A3 Q01959 12/20 0.50
KCNH2 Q12809 8/20 0.50
CYP3A4 P08684 2/20 0.50
HDAC1 Q13547 1/20 0.50
ATM Q13315 1/20 0.50
HDAC8 Q9BY41 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6490271 1.00 CYP2D6 (0.59) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL6543395 1.00 CYP2D6 (0.59) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL3266869 0.85 UGT2B7 (0.61) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL13801033 0.84 CYP2D6 (0.56) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL9043925 0.82 HDAC1 (0.57) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL10120474 0.82 UGT2B7 (0.62) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL4945583 0.82 SLC6A2 (0.62) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL483715 0.82 UGT2B7 (0.62) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL7229252 0.82 CYP2D6 (0.57) CYP2D6MEN1KMT2AAOC3CYP1A2
SCHEMBL894256 0.82 CYP2D6 (0.57) CYP2D6MEN1KMT2AAOC3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112409845-A Printing ink TCL集团股份有限公司 2021-02-26 CN claimed
CN-112409845-B Printing ink TCL科技集团股份有限公司 2022-03-01 CN disclosed
CN-112409845-A Printing ink TCL集团股份有限公司 2021-02-26 CN disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
EP-3315531-A1 8-ARM POLYETHYLENE GLYCOL DERIVATIVE, MANUFACTURING METHOD AND MODIFIED BIO-RELATED SUBSTANCE THEREBY Xiamen Sinopeg Biotech Co., Ltd. (CN) 2018-05-02 EP disclosed
CN-104877127-B A kind of eight arms polyethyleneglycol derivative, preparation method and its bio-related substance of modification 厦门赛诺邦格生物科技股份有限公司 2017-11-10 CN disclosed
CN-104877127-A Eight-armed polyethylene glycol derivative, preparation method and related biological substance modified by derivative XIAMEN SINOPEG BIOTECH CO LTD 2015-09-02 CN disclosed
US-9023652-B2 Organometallic sensor device UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) 2015-05-05 US disclosed
WO-2008078092-A1 FERROCENYL BORONIC ACID BASED SENSOR FOR FLUORIDE AND CYANIDE UNIVERSITY COLLEGE CARDIFF CONSULTANTS LTD. (GB) 2008-07-03 WO disclosed
EP-1175382-B1 METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS BAYER CHEMICALS AG (DE) 2005-02-09 EP disclosed
US-6825377-B1 CATALYTIC OXIDATION USING OXYGEN OR GAS MIXTURE IN PRESENCE OF OSMIUM, RUTHENIUM, OR MANGANESE COMPOUND IN WATER; ADDING AMINE FOR CATALYST SELECTIVITY BAYER AKTIENGESELLSCHAFT (DE) 2004-11-30 US disclosed
CN-1174103-C Process for preparing chiral substituted arylepoxyethane compounds and its biol by selective splitting of Aspergillus niger 中国科学院上海有机化学研究所 2004-11-03 CN disclosed
EP-1404687-A4 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIV PITTSBURGH (US) 2004-10-27 EP disclosed
EP-1404687-A2 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIVERSITY OF PITTSBURGH (US) 2004-04-07 EP disclosed
WO-2002100802-A2 FLUOROUS TRIPHASE AND OTHER MULTIPHASE SYSTEMS UNIVERSITY OF PITTSBURGH (US) 2002-12-19 WO disclosed
CN-1369565-A Process for preparing chiral substituted arylepoxyethane compounds and its biol by selective splitting of Aspergillus niger SHANGHAI INST ORGANIC CHEM (CN) 2002-09-18 CN disclosed
EP-1175382-A1 METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS Bayer Aktiengesellschaft (DE) 2002-01-30 EP disclosed
WO-2000064848-A1 METHOD FOR THE DIHYDROXYLATION OF OLEFINS USING TRANSITION-METAL CATALYSTS BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A CYP2D6 1493/4885MEN1 1772/4885KMT2A 4271/4885
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 CYP2D6 1072/4885MEN1 1107/4885KMT2A 4046/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 CYP2D6 1225/4885MEN1 2488/4885KMT2A 3943/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.