Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GMNN | O75496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5597866 | 0.76 | CYP2C9 (0.36) | CYP2C9HSD11B1 | |
| SCHEMBL7445783 | 0.76 | CYP2C9 (0.36) | CYP2C9HSD11B1 | |
| SCHEMBL12765810 | 0.76 | EPHX2 (0.34) | TP53KDM4EGMNNLMNAMAPT | |
| SCHEMBL1782725 | 0.73 | CYP2C9 (0.32) | CYP2C9 | |
| SCHEMBL3279708 | 0.72 | CYP2C9 (0.41) | CYP2C9HSD11B1EPHX1 | |
| SCHEMBL353657 | 0.68 | — | — | |
| Acetic Acid SCHEMBL6425310 | 0.67 | HSD11B1 (0.38) | HSD11B1EPHX1ALDH1A1 | |
| SCHEMBL2995688 | 0.67 | CYP2C9 (0.41) | CYP2C9HSD11B1EPHX1 | |
| SCHEMBL679325 | 0.67 | CYP2C9 (0.41) | CYP2C9HSD11B1EPHX1 | |
| SCHEMBL3279703 | 0.67 | CYP2C9 (0.41) | CYP2C9HSD11B1EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385064-B1 | Catalysts for use in enantioselective synthesis | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2008-06-10 | — | — | US | disclosed |