Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677067 | 0.77 | MEN1 (0.39) | CYP2C9EPHX1EPHX2 | |
| SCHEMBL3279703 | 0.72 | CYP2C9 (0.41) | CYP2C9EPHX1EPHX2HSD11B1 | |
| SCHEMBL6655791 | 0.72 | CYP2C9 (0.35) | CYP2C9EPHX1EPHX2 | |
| SCHEMBL2995688 | 0.72 | CYP2C9 (0.41) | CYP2C9EPHX1EPHX2HSD11B1 | |
| SCHEMBL3279708 | 0.72 | CYP2C9 (0.41) | CYP2C9EPHX1EPHX2HSD11B1 | |
| SCHEMBL25465432 | 0.72 | CYP2C9 (0.35) | CYP2C9EPHX1EPHX2 | |
| SCHEMBL7714569 | 0.72 | CYP2C9 (0.35) | CYP2C9EPHX1EPHX2 | |
| SCHEMBL1548216 | 0.72 | SLC22A2 (0.39) | CYP2C9EPHX1EPHX2 | |
| SCHEMBL26741944 | 0.72 | SLC22A2 (0.39) | CYP2C9EPHX1EPHX2 | |
| SCHEMBL8090288 | 0.71 | SLC22A2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912647-B2 | Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2024-02-27 | — | — | US | disclosed |
| CN-114716296-B | Efficient halogenation synthesis method of alkyl halide | 润药仁智(北京)科技有限公司 | 2023-12-12 | — | — | CN | disclosed |
| US-20210363098-A1 | DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2021-11-25 | — | — | US | disclosed |
| CN-107556244-B | Fused ring compound, pharmaceutical composition and application thereof | 上海迪诺医药科技有限公司 | 2021-09-03 | — | — | CN | disclosed |
| US-20160237084-A1 | DIHYDRO-PYRROLOPYRIDINONE INHIBITORS | ABBVIE INC (US) | 2016-08-18 | — | — | US | disclosed |
| US-9321764-B2 | Dihydro-pyrrolopyridinone inhibitors | ABBVIE INC. (US) | 2016-04-26 | — | — | US | disclosed |
| EP-2970276-A1 | DIHYDRO-PYRROLOPYRIDINONE BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| CN-105164130-A | Dihydro-pyrrolopyridone bromodomain inhibitors | ABBVIE INC | 2015-12-16 | — | — | CN | disclosed |
| CN-104844532-A | Antiviral compounds, and preparation method and use thereof | ZHOU JINGYE | 2015-08-19 | — | — | CN | disclosed |
| CN-104136471-A | (meth) acrylate composition, resin, and molded body | IDEMITSU KOSAN CO | 2014-11-05 | — | — | CN | disclosed |
| EP-1789085-A2 | CHANGE OF THE LOAD STATE OF MHC MOLECULES | MAX-DELBRÜCK-CENTRUM FÜR MOLEKULARE MEDIZIN (DE) | 2007-05-30 | — | — | EP | disclosed |
| US-20070015026-A1 | Membrane-electrode assembly for solid polymer electrolyte fuel cell | HONDA MOTOR CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-08-24 | — | — | US | disclosed |
| WO-2006029891-A2 | CHANGE OF THE LOAD STATE OF MHC MOLECULES | Max-Delbrück-Centrum für Molekulare Medizin (DE) | 2006-03-23 | — | — | WO | disclosed |
| EP-0661271-B1 | AZEPINE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS SIGMA-RECEPTOR LIGANDS | ASAHI CHEMICAL IND (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5658923-A | USED IN TREATING DISEASES RELATED TO SIGMA-RECEPTOR, SUCH AS SCHIZOPHRENIA | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1997-08-19 | — | — | US | disclosed |
| EP-0661271-A1 | AZEPINE DERIVATIVE, PRODUCTION THEREOF, AND USE THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-4849172-A | Optical sensor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1989-07-18 | — | — | US | disclosed |
| CN-87104184-A | PHOTOCHROMIC SPIROPYRAN COMPOUNDS | — | 1988-06-29 | — | — | CN | disclosed |
| EP-0243116-A2 | Optical sensor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363098-A1 | DIVERSITY-ORIENTED SYNTHESIS OF N,N,O-TRISUBSTITUTED HYDROXYLAMINES FROM ALCOHOLS AND AMINES BY N-O BOND FORMATION | ADH5, ADH1A, NAT1 | CYP2C9 298/4885EPHX1 1040/4885EPHX2 787/4885 |
| US-20160237084-A1 | DIHYDRO-PYRROLOPYRIDINONE INHIBITORS | DPYD, QDPR, DHFR | CYP2C9 649/4885EPHX1 875/4885EPHX2 2083/4885 |
| US-11912647-B2 | Diversity-oriented synthesis of N,N,O-trisubstituted hydroxylamines from alcohols and amines by N—O bond formation | ADH5, ADH1A, NAT1 | CYP2C9 282/4885EPHX1 1088/4885EPHX2 863/4885 |
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | ALDH3A1, ALDH1A1, POLL | CYP2C9 2615/4885EPHX1 436/4885EPHX2 609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.