Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584989 | 0.82 | ALDH1A1 (0.66) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL4951448 | 0.79 | ALDH1A1 (0.47) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| Methylene Chloride SCHEMBL28345680 | 0.78 | ALDH1A1 (0.60) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL28342966 | 0.75 | KMT2A (0.42) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL18525769 | 0.75 | HSD17B10 (0.44) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL14144960 | 0.72 | CYP1A2 (0.47) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL28572451 | 0.72 | HPGD (0.53) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL2123580 | 0.71 | HPGD (0.73) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL9764099 | 0.71 | ALDH1A1 (0.63) | HPGDALDH1A1KMT2AHSD17B10KDM4E | |
| SCHEMBL1976674 | 0.70 | ALDH1A1 (0.49) | HPGDALDH1A1KMT2AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8557565-B2 | Degradation of polycyclic aromatic hydrocarbons to render them available for biodegradation | WAVREK DAVID (US) | 2013-10-15 | — | — | US | disclosed |
| US-8298814-B1 | Degradation of polycyclic aromatic hydrocarbons | Wavrek, David A. (US) | 2012-10-30 | — | — | US | disclosed |
| US-20080242875-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION | HONG P K ANDY | 2008-10-02 | — | — | US | disclosed |
| EP-1230400-B1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIV UTAH RES FOUND (US) | 2008-09-24 | — | — | EP | disclosed |
| EP-1230400-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | University of Utah Research Foundation (US) | 2002-08-14 | — | — | EP | disclosed |
| WO-2001032936-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2001-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080242875-A1 | DEGRADATION OF POLYCYCLIC AROMATIC HYDROCARBONS TO RENDER THEM AVAILABLE FOR BIODEGRADATION | PAH, AHR, TDO2 | HPGD 1167/4885ALDH1A1 3754/4885KMT2A 4179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.