SCHEMBL4948140

SCHEMBL4948140

C=C(C(=O)O)C(C)N(C)C.CCCCCCCCCCCCCCCCCl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.43
ALDH1A1 P00352 3/20 0.43
FAAH O00519 1/20 0.37
ACE2 Q9BYF1 1/20 0.35
GPR84 Q9NQS5 9/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
PTPN1 P18031 3/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
FABP4 P15090 2/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
SLC22A8 Q8TCC7 1/20 0.34
MEN1 O00255 1/20 0.34
ESR1 P03372 1/20 0.34
ALOX15 P16050 1/20 0.34
PDE4A P27815 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9436752 0.83 PPARD (0.37) TSHRALDH1A1ACE2GPR84PPARG
SCHEMBL27651631 0.82 TSHR (0.44) TSHRALDH1A1FAAHACE2GPR84
Hydrochloric Acid SCHEMBL27886679 0.81 TSHR (0.43) TSHRALDH1A1FAAHACE2GPR84
Chloromethane SCHEMBL124970 0.78 LMNA (0.30)
SCHEMBL186411 0.78 LMNA (0.32) TDP1
SCHEMBL4172312 0.74 TSHR (0.41) TSHRALDH1A1FAAHACE2GPR84
SCHEMBL4164364 0.74 TSHR (0.41) TSHRALDH1A1FAAHACE2GPR84
SCHEMBL4164311 0.74 TSHR (0.41) TSHRALDH1A1FAAHACE2GPR84
SCHEMBL4173877 0.74 TSHR (0.41) TSHRALDH1A1FAAHACE2GPR84
SCHEMBL4162118 0.74 TSHR (0.41) TSHRALDH1A1FAAHACE2GPR84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6426383-B1 POLYMERIZING NONIONIC POLYVINYLACETAMIDE DISPERSED IN AQUEOUS SOLUTION CONTAINING POLYVINYL ALCOHOL AS STABILIZER NALCO CHEMICAL COMPANY 2002-07-30 US claimed
US-6133368-A A FIRST DISPERSANT POLYMER IS A COPOLYMER OF DIALLYLDIMETHYLAMMONIUM CHLORIDE AND A SECOND MONOMER ISDIMETHYLAMINOETHYL(METH)ACRYALTE BENZYL OR CETYL CHLORIDE QUATERNARY AND ETHYLHEXYL ACRYLATE, A SECOND CATIONIC POLYMER NALCO CHEMICAL COMPANY (US) 2000-10-17 US claimed
EP-0643017-B1 Hydrophobic Polyelectrolyte coagulants for concentrating coal tailings NALCO CHEMICAL CO (US) 1997-12-17 EP claimed
EP-0637598-B1 Hydrophobic dispersants used in forming polymer dispersions NALCO CHEMICAL CO (US) 1997-05-02 EP claimed
US-5597859-A FORMING DIALKYLAMINOALKYL(METH)ACYLAMIDE POLYMER DISPERSIONS NALCO CHEMICAL COMPANY (US) 1997-01-28 US claimed
US-5435922-A Acrylic quaternary ammonium polymer NALCO CHEMICAL COMPANY (US) 1995-07-25 US claimed
EP-0643017-A1 Hydrophobic Polyelectrolyte coagulants for concentrating coal tailings NALCO CHEMICAL COMPANY (US) 1995-03-15 EP claimed
EP-0637598-A2 Hydrophobic dispersants used in forming polymer dispersions NALCO CHEMICAL COMPANY (US) 1995-02-08 EP claimed
US-5338816-A Treating paper mill waste water with a copolymer of diallyldimethylammonium chloride and a hydrophobic quaternized dimethylaminoethyl(meth)acrylate NALCO CHEMICAL COMPANY (US) 1994-08-16 US claimed
US-5330546-A Copolymer of diallyldimethylammonium chloride and a quaternary of a dialkylaminoethyl /meth/acrylate; flocculant NALCO CHEMICAL COMPANY (US) 1994-07-19 US claimed
US-5314627-A Papermaking NALCO CHEMICAL COMPANY (US) 1994-05-24 US claimed
US-5292793-A Copolymer of acrylamide and a quaternized dimethylaminoethyl acrylate NALCO CHEMICAL COMPANY (US) 1994-03-08 US claimed
US-5283306-A Diallyldimethylammonium chloride copolymerized with dimethylaminoethyl(meth)acrylate that has been quaternized NALCO CHEMICAL COMPANY (US) 1994-02-01 US claimed
US-5246547-A Antideposit, cationic polymers NALCO CHEMICAL COMPANY (US) 1993-09-21 US claimed
US-20220228019-A1 HYDROPHILIC CATIONIC DISPERSION POLYMERS FOR IMPROVED PRINT QUALITY AND WATER FASTNESS ECOLAB USA INC. (US) 2022-07-21 US disclosed
EP-3980500-A1 HYDROPHILIC CATIONIC DISPERSION POLYMERS FOR IMPROVED PRINT QUALITY AND WATER FASTNESS ECOLAB USA INC. (US) 2022-04-13 EP disclosed
WO-2020247637-A1 HYDROPHILIC CATIONIC DISPERSION POLYMERS FOR IMPROVED PRINT QUALITY AND WATER FASTNESS ECOLAB USA INC. (US) 2020-12-10 WO disclosed
US-5292793-A Copolymer of acrylamide and a quaternized dimethylaminoethyl acrylate NALCO CHEMICAL COMPANY (US) 1994-03-08 US disclosed
US-5283306-A Diallyldimethylammonium chloride copolymerized with dimethylaminoethyl(meth)acrylate that has been quaternized NALCO CHEMICAL COMPANY (US) 1994-02-01 US disclosed
US-5246547-A Antideposit, cationic polymers NALCO CHEMICAL COMPANY (US) 1993-09-21 US disclosed