Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.37 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.34 |
| ▸ | PPARG | P37231 | 7/20 | 0.34 |
| ▸ | PPARA | Q07869 | 7/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TLR2 | O60603 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.34 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948140 | 0.83 | TSHR (0.43) | PPARDACE2GPR84PPARGPPARA | |
| Bromomethane SCHEMBL7095820 | 0.78 | LMNA (0.30) | LMNA | |
| SCHEMBL186411 | 0.78 | LMNA (0.32) | LMNATDP1 | |
| Methacrylic Acid SCHEMBL28739443 | 0.76 | TSHR (0.47) | PPARDGPR84PPARGPPARAHDAC11 | |
| Methacrylic Acid SCHEMBL28041673 | 0.76 | TSHR (0.47) | PPARDGPR84PPARGPPARAHDAC11 | |
| Hydrochloric Acid SCHEMBL28878591 | 0.75 | LMNA (0.31) | LMNA | |
| SCHEMBL9436706 | 0.74 | PPARD (0.35) | PPARDLCKZDHHC20ZDHHC2LMNA | |
| SCHEMBL8762013 | 0.74 | PPARD (0.35) | PPARDLCKZDHHC20ZDHHC2LMNA | |
| SCHEMBL28025488 | 0.74 | ACE2 (0.48) | PPARDLCKZDHHC20ZDHHC2ACE2 | |
| Dodecane SCHEMBL27603441 | 0.74 | ACE2 (0.48) | PPARDLCKZDHHC20ZDHHC2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5314627-A | Papermaking | NALCO CHEMICAL COMPANY (US) | 1994-05-24 | — | — | US | claimed |
| US-5292793-A | Copolymer of acrylamide and a quaternized dimethylaminoethyl acrylate | NALCO CHEMICAL COMPANY (US) | 1994-03-08 | — | — | US | claimed |
| US-5314627-A | Papermaking | NALCO CHEMICAL COMPANY (US) | 1994-05-24 | — | — | US | disclosed |
| US-5292793-A | Copolymer of acrylamide and a quaternized dimethylaminoethyl acrylate | NALCO CHEMICAL COMPANY (US) | 1994-03-08 | — | — | US | disclosed |