Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | GRM6 | O15303 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953419 | 0.82 | PTGS1 (0.39) | ESR2PTGS1ALOX5APFEN1CYP1A2 | |
| SCHEMBL4950501 | 0.82 | PTGS1 (0.39) | ESR2PTGS1CYP1A2CYP3A4ALDH1A1 | |
| SCHEMBL4948327 | 0.81 | STS (0.49) | ESR2PTGS1ALDH1A1CLK4 | |
| SCHEMBL4948367 | 0.80 | ESR2 (0.43) | ESR2PTGS1MEN1KMT2APTGS2 | |
| SCHEMBL4950454 | 0.80 | PTGS1 (0.50) | PTGS1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL4948155 | 0.80 | ESR2 (0.50) | ESR2PTPN5PTGS1ALDH1A1MAPK1 | |
| SCHEMBL4359377 | 0.76 | ESR2 (0.66) | ESR2PTPN5ALOX5APFEN1TRPA1 | |
| SCHEMBL8382823 | 0.76 | ESR2 (0.47) | ESR2PTPN5PTGS1CYP1A2ALDH1A1 | |
| SCHEMBL31410710 | 0.75 | ESR2 (0.76) | ESR2PTPN5ALOX5APFEN1TRPA1 | |
| SCHEMBL4950460 | 0.74 | VCAM1 (0.42) | CYP3A4ALDH1A1MEN1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |