Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 9/20 | 0.43 |
| ▸ | ESR1 | P03372 | 9/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ESRRB | O95718 | 1/20 | 0.33 |
| ▸ | ESRRA | P11474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4953419 | 0.86 | PTGS1 (0.39) | ESR2PTGS1MEN1KMT2ASTS | |
| SCHEMBL4948327 | 0.84 | STS (0.49) | ESR2PTGS1STS | |
| SCHEMBL4950454 | 0.83 | PTGS1 (0.50) | PTGS1PTGS2 | |
| SCHEMBL4948364 | 0.83 | ESR2 (0.40) | ESR2ESR1ARCYP19A1PTGS1 | |
| SCHEMBL4950921 | 0.81 | PTGS1 (0.46) | PTGS1STS | |
| SCHEMBL4948159 | 0.80 | ESR2 (0.51) | ESR2PTGS1PTGS2MEN1KMT2A | |
| SCHEMBL4951189 | 0.78 | PTGS1 (0.34) | PTGS1STS | |
| SCHEMBL4945657 | 0.78 | VCAM1 (0.45) | MEN1KMT2A | |
| SCHEMBL4950501 | 0.77 | PTGS1 (0.39) | ESR2PTGS1MEN1KMT2A | |
| SCHEMBL4947779 | 0.75 | SCN9A (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |