Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | CASP6 | P55212 | 1/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | TPMT | P51580 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566129 | 0.87 | THRA (0.56) | TSHRPOLBCASP6CREBBPTHRA | |
| SCHEMBL29010144 | 0.86 | CREBBP (0.66) | TSHRCREBBPNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3997365 | 0.86 | TSHR (0.66) | TSHRPOLBCASP6CREBBPNPC1 | |
| SCHEMBL25788109 | 0.84 | THRA (0.68) | TSHRTHRATHRB | |
| SCHEMBL25788111 | 0.84 | THRA (0.68) | TSHRTHRATHRB | |
| SCHEMBL25788106 | 0.84 | THRA (0.68) | TSHRTHRATHRB | |
| SCHEMBL25788104 | 0.84 | THRA (0.68) | TSHRTHRATHRB | |
| SCHEMBL29882038 | 0.84 | TSHR (0.83) | TSHRPOLBCASP6CREBBPNPC1 | |
| SCHEMBL177424 | 0.84 | TSHR (0.83) | TSHRPOLBCASP6CREBBPNPC1 | |
| SCHEMBL3410155 | 0.83 | MGLL (0.56) | TSHRCREBBPNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023150197-A1 | ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF | NEXYS THERAPEUTICS, INC. (US) | 2023-08-10 | — | — | WO | disclosed |
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |