Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | PREP | P48147 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2434336 | 0.79 | HSD17B10 (0.38) | HPGDSMN1; SMN2CHRM3 | |
| SCHEMBL72410 | 0.78 | DGAT1 (0.38) | DGAT1HPGDUSP2SMN1; SMN2CTSK | |
| SCHEMBL2432116 | 0.78 | SMN1; SMN2 (0.38) | DGAT1HPGDSMN1; SMN2EPHX1 | |
| SCHEMBL2432683 | 0.77 | KDM4E (0.41) | SMN1; SMN2 | |
| SCHEMBL2433990 | 0.76 | DGAT1 (0.35) | DGAT1HPGDUSP2SMN1; SMN2CTSK | |
| SCHEMBL18921418 | 0.75 | CTSK (0.42) | DGAT1HPGDUSP2SMN1; SMN2CTSK | |
| SCHEMBL28750768 | 0.73 | DGAT1 (0.36) | DGAT1HPGDUSP2SMN1; SMN2CTSK | |
| SCHEMBL2433463 | 0.73 | DGAT1 (0.36) | DGAT1HPGDUSP2SMN1; SMN2CTSK | |
| SCHEMBL5155312 | 0.72 | CA1 (0.43) | HPGDSMN1; SMN2 | |
| SCHEMBL3163754 | 0.72 | HPGD (0.38) | DGAT1HPGDUSP2SMN1; SMN2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |
| EP-1961750-A1 | VLA-4 INHIBITORY DRUG | Daiichi Sankyo Company, Limited (JP) | 2008-08-27 | — | — | EP | disclosed |