SCHEMBL4948416

SCHEMBL4948416

C=CCOP(=O)(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
PKM P14618 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
CYP3A4 P08684 1/20 0.44
TSHR P16473 2/20 0.44
ALOX15 P16050 1/20 0.44
ALDH1A1 P00352 5/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
LIG1 P18858 1/20 0.40
ELANE P08246 1/20 0.40
CA2 P00918 2/20 0.39
HSD17B10 Q99714 1/20 0.39
CFTR P13569 1/20 0.38
AOX1 Q06278 1/20 0.38
LMNA P02545 1/20 0.37
ACHE P22303 1/20 0.37
CA4 P22748 1/20 0.37
CA5A P35218 1/20 0.37
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL331731 0.84 PKM (0.49) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL3893776 0.82 MEN1 (0.55) MEN1KMT2APKMTSHRALOX15
SCHEMBL8652973 0.81 PKM (0.46) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL3468614 0.81 TSHR (0.50) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL28512677 0.81 MEN1 (0.59) MEN1KMT2APKMSMN1; SMN2TSHR
Vinyl Chloride SCHEMBL11613404 0.79 PKM (0.45) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL11319680 0.79 SMN1; SMN2 (0.45) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL9940137 0.79 PKM (0.45) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL11325269 0.78 PKM (0.44) MEN1KMT2APKMSMN1; SMN2CYP3A4
SCHEMBL8741331 0.77 L3MBTL1 (0.61) MEN1KMT2APKMSMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372383-B Preparation method of organic phosphate compound 中南大学 2022-08-02 CN disclosed
CN-113736075-B Preparation method of polylactone 深圳大学 2022-06-24 CN disclosed
CN-113736075-A Preparation method of polylactone 深圳大学 2021-12-03 CN disclosed
CN-113372383-A Preparation method of organic phosphate compound 中南大学 2021-09-10 CN disclosed
US-9051629-B2 Process for separating americium from other metallic elements present in an acidic aqueous or organic phase COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-09 US disclosed
US-20130259776-A1 PROCESS FOR SEPARATING AMERICUM FROM OTHER METALLIC ELEMENTS PRESENT IN AN ACIDIC AQUEOUS OR ORGANIC PHASE AND APPLICATIONS THEREOF AREVA NC (FR) 2013-10-03 US disclosed
US-7468225-B2 Non-aqueous electrolyte secondary battery PANASONIC CORPORATION (JP) 2008-12-23 US disclosed
US-20070218370-A1 NonAqueous Electrolyte Secondary Battery PANASONIC CORPORATION (JP) 2007-09-20 US disclosed
US-6399731-B2 SYNTHESIZING POLYMERS USING PHOSPHOROUS-CONTAINING ADDITION-FRAGMENTATION CHAIN TRANSFER AGENTS; MOLECULAR WEIGHT CONTROL THE UNIVERSITY OF AKRON 2002-06-04 US disclosed
US-20020016424-A1 Synthesizing polymers using phosphorous-containing addition-fragmentation chain transfer agents; molecular weight control AKRON, THE UNIVERSITY OF 2002-02-07 US disclosed
WO-2000020465-A1 NOVEL CHAIN TRANSFER AGENTS THE UNIVERSITY OF AKRON (US) 2000-04-13 WO disclosed