SCHEMBL4948726

SCHEMBL4948726

CCCC(Oc1ccc(N)cc1)Oc1ccc(N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.48
TSHR P16473 4/20 0.48
MAPK1 P28482 3/20 0.43
ALDH1A1 P00352 6/20 0.41
CYP3A4 P08684 4/20 0.41
MAPT P10636 5/20 0.39
RAB9A P51151 3/20 0.39
NPC1 O15118 2/20 0.39
TEAD4 Q15561 1/20 0.39
POLB P06746 1/20 0.38
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
PDE4D Q08499 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
MAOA P21397 3/20 0.35
HPGD P15428 1/20 0.35
NR4A1 P22736 1/20 0.35
APP P05067 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2535207 0.88 TDP1 (0.45) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL21694050 0.87 CYP3A4 (0.49) TDP1TSHRALDH1A1CYP3A4MAPT
SCHEMBL10595641 0.86 TDP1 (0.44) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL21693953 0.85 SKP2 (0.38) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL21694074 0.85 CYP1A2 (0.46) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL21693976 0.85 CASP1 (0.43) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL25283342 0.85 SLC2A1 (0.44) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL15939864 0.85 SLC2A1 (0.44) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL12112116 0.85 SLC2A1 (0.44) TDP1TSHRMAPK1ALDH1A1CYP3A4
SCHEMBL7908097 0.85 SLC2A1 (0.44) TDP1TSHRMAPK1ALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3642262-A1 CURABLE POLYIMIDES Designer Molecules, Inc. (US) 2020-04-29 EP claimed
WO-2018237377-A1 CURABLE POLYIMIDES DESIGNER MOLECULES, INC (US) 2018-12-27 WO claimed
WO-2008092168-A2 METHODS FOR THE PREPARATION OF IMIDES, MALEIMIDES AND MALEIMIDE-TERMINATED POLYIMIDE COMPOUNDS DESIGNER MOLECULES, INC. (US) 2008-07-31 WO claimed
CN-111448510-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2023-03-14 CN disclosed
CN-111433665-B Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2023-02-28 CN disclosed
CN-114901362-A Bivalent LECA inhibitors against pseudomonas aeruginosa biofilm formation 赫姆霍尔兹传染病研究中心有限责任公司 2022-08-12 CN disclosed
CN-111448510-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2020-07-24 CN disclosed
CN-111433665-A Liquid crystal aligning agent, liquid crystal alignment film, liquid crystal element, and method for producing liquid crystal element JSR株式会社 2020-07-17 CN disclosed
CN-105733610-B Composition containing polyamic acid polymer, liquid crystal aligning agent, liquid crystal aligning film and liquid crystal display element JSR株式会社 2019-12-17 CN disclosed
US-20140226116-A1 LIQUID CRYSTAL DISPLAY AND METHOD FOR PRODUCING LIQUID CRYSTAL DISPLAY JSR CORPORATION (JP) 2014-08-14 US disclosed
US-8053041-B2 Overcoat film composition, color filter substrate, and liquid crystal display element JNC CORPORATION (JP) 2011-11-08 US disclosed
WO-2008092168-A2 METHODS FOR THE PREPARATION OF IMIDES, MALEIMIDES AND MALEIMIDE-TERMINATED POLYIMIDE COMPOUNDS DESIGNER MOLECULES, INC. (US) 2008-07-31 WO disclosed
US-20080167429-A1 Nanoimprinting composition CHISSO CORPORATION 2008-07-10 US disclosed
US-20080003381-A1 Overcoat film composition, color filter substrate, and liquid crystal display element CHISSO CORPORATION 2008-01-03 US disclosed
EP-0262513-A1 Polyimides and method for making GENERAL ELECTRIC COMPANY (US) 1988-04-06 EP disclosed