Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 19/20 | 0.71 |
| ▸ | PDE4A | P27815 | 3/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.51 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4944841 | 0.96 | PDE4B (0.77) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL4946547 | 0.95 | PDE4B (0.77) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4952294 | 0.92 | PDE4B (0.66) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL4949150 | 0.89 | PDE4B (0.64) | PDE4BPDE4APDE4CPDE4DCSF1R | |
| SCHEMBL4946407 | 0.89 | PDE4B (0.66) | PDE4BCSF1R | |
| SCHEMBL4949236 | 0.89 | PDE4B (0.66) | PDE4BCSF1R | |
| SCHEMBL4952552 | 0.88 | PDE4B (0.65) | PDE4BCSF1R | |
| SCHEMBL2478883 | 0.88 | PDE4B (0.92) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4946623 | 0.87 | PDE4B (0.73) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL4949534 | 0.87 | PDE4B (0.63) | PDE4BPDE4APDE4CPDE4DCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633748-B1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-03-05 | — | — | EP | claimed |