Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3011348 | 0.96 | ALDH1A1 (0.31) | ALDH1A1TDP1EIF2AK2CSNK2A2CSNK2B | |
| SCHEMBL9780554 | 0.89 | EIF2AK2 (0.32) | ALDH1A1TDP1EIF2AK2CSNK2A2CSNK2B | |
| SCHEMBL4951332 | 0.83 | ALDH1A1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL4950368 | 0.82 | TAAR1 (0.33) | — | |
| SCHEMBL4952593 | 0.80 | — | — | |
| SCHEMBL28392904 | 0.79 | TDP1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL29446475 | 0.79 | TDP1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL4810985 | 0.79 | TDP1 (0.32) | ALDH1A1TDP1 | |
| SCHEMBL8854109 | 0.77 | KCNN4 (0.39) | ALDH1A1TDP1 | |
| SCHEMBL1226128 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378449-B2 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION (US) | 2008-05-27 | — | — | US | disclosed |
| US-20070093582-A1 | POLY(BROMOARYL)ALKANE ADDITIVES AND METHODS FOR THEIR PREPARATION AND USE | ALBEMARLE CORPORATION (US) | 2007-04-26 | — | — | US | disclosed |
| US-7129385-B2 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION (US) | 2006-10-31 | — | — | US | disclosed |
| US-20040195087-A1 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION | 2004-10-07 | — | — | US | disclosed |
| US-6743825-B1 | Poly(bromoaryl)alkane additives and methods for their preparation and use | ALBEMARLE CORPORATION | 2004-06-01 | — | — | US | disclosed |