SCHEMBL9780554

SCHEMBL9780554

Brc1cc(C(Br)(Br)C(Br)(Br)c2ccccc2)c(Br)c(Br)c1Br

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
EIF2AK2 P19525 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
CSNK2A1 P68400 1/20 0.32
KCNN4 O15554 2/20 0.31
TDP1 Q9NUW8 1/20 0.31
TSHR P16473 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3011348 0.89 ALDH1A1 (0.31) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL4948749 0.89 ALDH1A1 (0.31) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1
SCHEMBL4950368 0.85 TAAR1 (0.33) KCNN4
SCHEMBL4952593 0.83
SCHEMBL4810985 0.82 TDP1 (0.32) KCNN4TDP1TSHRALDH1A1
SCHEMBL28392904 0.82 TDP1 (0.32) KCNN4TDP1TSHRALDH1A1
SCHEMBL29446475 0.82 TDP1 (0.32) KCNN4TDP1TSHRALDH1A1
SCHEMBL8854109 0.80 KCNN4 (0.39) KCNN4TDP1TSHRALDH1A1
SCHEMBL4949412 0.78 TDP1 (0.30) TDP1
SCHEMBL10881874 0.78 CYP2C19 (0.33) EIF2AK2CSNK2A2CSNK2BCSNK2A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4981890-A POLYHALOAROMATIC AND AROMATIC BIS-SULFONAMIDE ETHYL CORPORATION (US) 1991-01-01 US disclosed
US-4957957-A Polymer compositions containing aromatic sulfonamide ETHYL CORPORATION (US) 1990-09-18 US disclosed