Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 9/20 | 0.41 |
| ▸ | FEN1 | P39748 | 8/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4234360 | 0.84 | DPP4 (0.50) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL16009843 | 0.79 | PTGS1 (0.41) | PTGS1MEN1PTGS2KMT2AFABP2 | |
| SCHEMBL10429634 | 0.77 | RARB (0.49) | ALOX5APFEN1 | |
| SCHEMBL7348409 | 0.75 | TAAR1 (0.39) | LMNAMAPTHIF1A | |
| SCHEMBL27360818 | 0.75 | DPP4 (0.47) | PTGER1PTGER4PTGER3PTGER2KMT2A | |
| SCHEMBL18002835 | 0.74 | RORC (0.45) | PTGER1PTGER4PTGER3PTGER2 | |
| SCHEMBL2474403 | 0.74 | PDE3B (0.45) | ALOX5APFEN1PTPRCPTPN1PDE3B | |
| SCHEMBL17951222 | 0.74 | PTPRC (0.58) | ALOX5APFEN1PTPRCPTPN1PDE3B | |
| SCHEMBL11453895 | 0.72 | GRIA4 (0.50) | PTPRCPTPN1MEN1KMT2ATSHR | |
| SCHEMBL19308531 | 0.72 | FEN1 (0.50) | ALOX5APFEN1PTPRCPTPN1PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008074717-A2 | PROCESS FOR THE PREPARATION OF CHIRAL 2-ARYLPROPANOLS HAVING A PROFEN-LIKE SUBSTITUTED ARYL RESIDUE | ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA (IT) | 2008-06-26 | — | — | WO | disclosed |