SCHEMBL7348409

SCHEMBL7348409

O=CCCc1ccccc1-c1ccccc1F

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.39
IDO1 P14902 2/20 0.37
LMNA P02545 1/20 0.34
CTSL P07711 1/20 0.34
CTSS P25774 1/20 0.34
CTSK P43235 1/20 0.34
HTR7 P34969 1/20 0.34
HIF1A Q16665 1/20 0.34
ACHE P22303 4/20 0.33
AOC3 Q16853 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MPO P05164 1/20 0.33
GPBAR1 Q8TDU6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373563 0.84 TAAR1 (0.56) TAAR1IDO1LMNAAOC3ALDH1A1
SCHEMBL2556909 0.84 TAAR1 (0.56) TAAR1IDO1LMNAAOC3ALDH1A1
SCHEMBL1515819 0.81 ACHE (0.38) TAAR1IDO1LMNACTSLCTSS
SCHEMBL28607303 0.77 ADH1B (0.36) TAAR1LMNAHIF1AALDH1A1MPO
SCHEMBL4234360 0.77 DPP4 (0.50) HTR7
SCHEMBL4846506 0.77 TAAR1 (0.38) TAAR1IDO1LMNACTSLCTSS
SCHEMBL3903028 0.76 TAAR1 (0.68) TAAR1IDO1AOC3MPO
SCHEMBL11453895 0.75 GRIA4 (0.50) ALDH1A1MAPTL3MBTL1
SCHEMBL4948853 0.75 ALOX5AP (0.41) LMNAHIF1AMAPT
SCHEMBL11805787 0.75 TAAR1 (0.43) TAAR1IDO1LMNAHTR7HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0766658-B1 PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES UNION CARBIDE CHEM PLASTIC (US) 2002-04-10 EP claimed
EP-0862549-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEM PLASTIC (US) 2000-05-31 EP claimed
US-5998660-A BY-PRODUCT INHIBITION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-12-07 US claimed
EP-0862549-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-09-09 EP claimed
US-5739385-A OXIDIZING AN OPTICALLY ACTIVE ALDEHYDE WITH A PERACID IN THE PRESENCE OF AN AMINE AND/OR AMINE N-OXIDE CATALYST UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-04-14 US claimed
US-5739352-A Process for preparing carboxylic acids UNITED CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-04-14 US claimed
WO-1997014669-A1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-04-24 WO claimed
EP-0766658-A1 PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1997-04-09 EP claimed
WO-1996000200-A1 PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1996-01-04 WO claimed
US-5430194-A Maintaining solution at temperature above eutectic temperature of mixture such that solubility limit of first aldehyde is exceeded to form crystalline first aldehyde containing less of second aldehyde UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1995-07-04 US claimed
EP-0766658-B1 PROCESS FOR IMPROVING ENANTIOMERIC PURITY OF ALDEHYDES UNION CARBIDE CHEM PLASTIC (US) 2002-04-10 EP disclosed
EP-0862549-B1 PROCESS FOR PREPARING OPTICALLY ACTIVE CARBOXYLIC ACIDS UNION CARBIDE CHEM PLASTIC (US) 2000-05-31 EP disclosed
US-5998660-A BY-PRODUCT INHIBITION UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-12-07 US disclosed
US-5739352-A Process for preparing carboxylic acids UNITED CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1998-04-14 US disclosed