Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.30 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291370 | 0.80 | PTGS1 (0.40) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL27860597 | 0.80 | MGLL (0.36) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL27663496 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL9636765 | 0.79 | GRM2 (0.36) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL26606118 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL27683092 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL26606120 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL27663503 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL27979483 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH | |
| SCHEMBL27660723 | 0.79 | MGLL (0.39) | GRM2PTGS1PTGS2MGLLFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319642-B1 | Method of Preparing a Halogenated Compound | OTSUKA KAGAKU KK (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0976700-B1 | PROCESS FOR HALOGENATING HYDROXYL GROUP | OTSUKA KAGAKU KK (JP) | 2004-07-28 | — | — | EP | disclosed |
| EP-1319642-A2 | Method of Preparing a Halogenated Compound | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2003-06-18 | — | — | EP | disclosed |
| US-6403789-B1 | REACTING IN ORGANIC SOLVENT DIALKYLHALOIMINIUM COMPOUND AS HALOGENATING AGENT AND LOWER ALKYL SULFONE, LOWER ALKENYL SULFONE, ARYL SULFONE OR HETEROCYCLIC SULFONE WITH HYDROXYL GROUP CONTAINING COMPOUND TO OBTAIN HALOGENIDE | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2002-06-11 | — | — | US | disclosed |
| US-6194567-B1 | PURITY OF HALOGENATED PRODUCT | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2001-02-27 | — | — | US | disclosed |
| EP-0976700-A1 | HALOGENATING AGENT AND PROCESS FOR HALOGENATING HYDROXYL GROUP | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 2000-02-02 | — | — | EP | disclosed |