Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL49494 | 0.91 | ESR1 (0.42) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL28443818 | 0.88 | ESR1 (0.40) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL709944 | 0.88 | ESR1 (0.40) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL9345851 | 0.88 | ESR1 (0.40) | ESR1ESR2ALDH1A1CES2CES1 | |
| Hydrochloric Acid SCHEMBL28156324 | 0.88 | ESR1 (0.40) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL28289364 | 0.88 | ESR1 (0.40) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL27700114 | 0.88 | ESR1 (0.40) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL11904130 | 0.85 | ESR1 (0.39) | ESR1ESR2ALDH1A1CES2CES1 | |
| SCHEMBL4276199 | 0.82 | ESR1 (0.48) | ESR1ESR2CES2CES1TSHR | |
| SCHEMBL4619383 | 0.82 | ESR1 (0.37) | ESR1ESR2ALDH1A1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5799705-A | Fire resistant pipe | AMERON INTERNATIONAL CORPORATION (US) | 1998-09-01 | — | — | US | disclosed |
| US-5758694-A | HELICALLY WOUND REINFORCING FIBER THAT IS BONDED TOGETHER WITH A THERMOSET POLYMER RESIN | AMERON INTERNATIONAL CORPORATION (US) | 1998-06-02 | — | — | US | disclosed |