Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 3/20 | 0.44 |
| ▸ | NOS1 | P29475 | 3/20 | 0.44 |
| ▸ | NOS2 | P35228 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4948541 | 0.83 | MEN1 (0.59) | MEN1KMT2ATDP1 | |
| SCHEMBL4955517 | 0.80 | CNR1 (0.47) | MEN1KMT2ACNR1CNR2MAPK14 | |
| SCHEMBL370543 | 0.78 | CNR1 (0.59) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL4246615 | 0.78 | NOS3 (0.62) | NOS3NOS1NOS2TDP1LTA4H | |
| Hydrochloric Acid SCHEMBL6247218 | 0.77 | CNR1 (0.58) | NOS3NOS1NOS2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5497258 | 0.77 | CNR1 (0.58) | NOS3NOS1NOS2MEN1KMT2A | |
| SCHEMBL4951898 | 0.75 | MEN1 (0.44) | NOS3NOS1NOS2IDO1EP300 | |
| SCHEMBL6162899 | 0.74 | NOS3 (0.48) | NOS3NOS1NOS2IDO1EP300 | |
| SCHEMBL11687927 | 0.72 | IDO1 (0.58) | IDO1EP300KAT8MEN1KMT2A | |
| SCHEMBL1803003 | 0.70 | CYP2C9 (0.62) | IDO1EP300KAT8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008089034-A2 | CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2008-07-24 | — | — | WO | disclosed |