Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20189792 | 0.80 | CYP11B2 (0.51) | GSK3AGSK3B | |
| SCHEMBL3224025 | 0.79 | ESR2 (0.60) | ESR2PDE10ATRPA1GSK3AGSK3B | |
| SCHEMBL31663514 | 0.79 | ESR2 (0.60) | ESR2PDE10ATRPA1GSK3AGSK3B | |
| SCHEMBL28162273 | 0.79 | CYP1A2 (0.45) | ESR2PDE10AALOX5APFEN1CYP1A2 | |
| SCHEMBL13316726 | 0.78 | HTT (0.50) | ESR2PDE10ATRPA1CYP1A2CYP3A4 | |
| SCHEMBL3791281 | 0.77 | ALDH1A1 (0.54) | GSK3BCYP1A2CYP3A4CYP2C19CYP2E1 | |
| SCHEMBL1146097 | 0.76 | CYP1A2 (0.57) | ESR2PDE10ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7215513 | 0.76 | ATR (0.50) | ESR2PDE10ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4359377 | 0.76 | ESR2 (0.66) | ESR2PDE10AALOX5APFEN1TRPA1 | |
| Hydrochloric Acid SCHEMBL16702548 | 0.76 | ALDH1A1 (0.52) | GSK3BCYP1A2CYP3A4CYP2C19CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |