Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.60 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 11/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482470 | 0.86 | PDE4B (0.60) | PDE4BMTNR1BCSF1RTHRB | |
| SCHEMBL4299487 | 0.86 | PDE4B (0.59) | PDE4BMTNR1BCSF1RCYP3A4CYP2C9 | |
| SCHEMBL4949101 | 0.84 | PDE4B (0.68) | PDE4BMTNR1BCSF1RTHRB | |
| Formic Acid SCHEMBL2479146 | 0.84 | PDE4B (0.57) | PDE4BMTNR1BCSF1RTHRB | |
| SCHEMBL4949711 | 0.83 | PDE4B (0.64) | PDE4BMTNR1BCSF1R | |
| SCHEMBL31020770 | 0.81 | PDE4B (0.61) | PDE4BMTNR1BCSF1RTHRB | |
| SCHEMBL4299675 | 0.80 | PDE4B (0.60) | PDE4BMTNR1BCSF1RCYP3A4CYP2C9 | |
| SCHEMBL4949741 | 0.80 | PDE4B (0.60) | PDE4BCSF1R | |
| SCHEMBL2479197 | 0.79 | PDE4B (0.66) | PDE4BCSF1R | |
| SCHEMBL2505851 | 0.79 | PDE4B (0.59) | PDE4BMTNR1BCSF1RTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633748-B1 | QUINOLINE DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | GLAXO GROUP LTD (GB) | 2008-03-05 | — | — | EP | claimed |