Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.45 |
| ▸ | FEN1 | P39748 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951169 | 0.86 | GRIA4 (0.51) | TDP1ALOX5APFEN1ALDH1A1L3MBTL1 | |
| SCHEMBL4953785 | 0.86 | ALOX5AP (0.55) | TDP1ALOX5APFEN1LMNAKMT2A | |
| SCHEMBL4950190 | 0.84 | TDP1 (0.61) | TDP1ALOX5APFEN1KDM4EALDH1A1 | |
| SCHEMBL4950018 | 0.83 | TDP1 (0.51) | TDP1ALOX5APFEN1LMNAMCL1 | |
| SCHEMBL4950547 | 0.83 | TDP1 (0.47) | TDP1ALOX5APFEN1MCL1TTR | |
| SCHEMBL4950475 | 0.82 | SRD5A2 (0.46) | SRD5A2TDP1KDM4ETTRGRIA4 | |
| SCHEMBL4952635 | 0.81 | TDP1 (0.50) | SRD5A2TDP1ALOX5APFEN1KDM4E | |
| SCHEMBL4953795 | 0.81 | TDP1 (0.47) | TDP1ALOX5APFEN1MCL1TTR | |
| SCHEMBL4947747 | 0.79 | TDP1 (0.53) | TDP1ALOX5APFEN1KDM4EALDH1A1 | |
| SCHEMBL6513336 | 0.78 | MCOLN3 (0.55) | TDP1ALOX5APFEN1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893597-B1 | AMPA RECEPTOR POTENTIATORS | LILLY CO ELI (US) | 2008-11-12 | — | — | EP | disclosed |