Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 20/20 | 0.58 |
| ▸ | GABRB3 | P28472 | 20/20 | 0.58 |
| ▸ | GABRA5 | P31644 | 20/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4951018 | 0.85 | GABRG2 (0.56) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4601740 | 0.85 | GABRG2 (0.56) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4946718 | 0.81 | GABRG2 (0.47) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4950870 | 0.80 | GABRG2 (0.61) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4947515 | 0.80 | GABRG2 (0.76) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4948510 | 0.80 | GABRG2 (0.48) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4946797 | 0.80 | GABRG2 (0.48) | GABRG2GABRB3GABRA5 | |
| SCHEMBL4952206 | 0.77 | GABRG2 (0.47) | GABRG2GABRB3GABRA5 | |
| SCHEMBL3582760 | 0.74 | GABRG2 (1.00) | GABRG2GABRB3GABRA5 | |
| SCHEMBL3884039 | 0.71 | GABRG2 (0.76) | GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809297-B1 | IMIDAZO[1,5A]TRIAZOLO[1,5D]BENZODIAZEPINE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DISORDERS | HOFFMANN LA ROCHE (CH) | 2008-07-30 | — | — | EP | claimed |
| EP-1809297-B1 | IMIDAZO[1,5A]TRIAZOLO[1,5D]BENZODIAZEPINE DERIVATIVES FOR THE TREATMENT OF COGNITIVE DISORDERS | HOFFMANN LA ROCHE (CH) | 2008-07-30 | — | — | EP | disclosed |