Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4950851 | 1.00 | MAPT (0.42) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL4950846 | 1.00 | MAPT (0.42) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL5787475 | 0.74 | THRA (0.42) | LMNAALDH1A1HIF1A | |
| SCHEMBL22201159 | 0.71 | KDM1A (0.44) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL21121183 | 0.71 | KDM1A (0.44) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL817759 | 0.70 | KDM1A (0.50) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL18086672 | 0.69 | KDM1A (0.39) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL28442251 | 0.69 | LMNA (0.49) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL16464448 | 0.68 | LMNA (0.54) | MAPTLMNAMEN1JAK2HTT | |
| SCHEMBL16464446 | 0.68 | LMNA (0.54) | MAPTLMNAMEN1JAK2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385064-B1 | Catalysts for use in enantioselective synthesis | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK | 2008-06-10 | — | — | US | disclosed |