Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.34 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095320 | 0.68 | LMNA (0.39) | F10 | |
| SCHEMBL4951845 | 0.67 | F10 (0.35) | F10 | |
| SCHEMBL1097360 | 0.64 | MIF (0.54) | F10 | |
| SCHEMBL1096582 | 0.60 | HPGD (0.43) | F10 | |
| SCHEMBL14085132 | 0.60 | TOP2A (0.44) | F10 | |
| SCHEMBL10313017 | 0.59 | MIF (0.68) | — | |
| SCHEMBL3089643 | 0.58 | HPGD (0.38) | F10 | |
| SCHEMBL1096416 | 0.57 | USP30 (0.40) | F10 | |
| SCHEMBL1096088 | 0.57 | F10 (0.42) | F10 | |
| SCHEMBL1096809 | 0.57 | LMNA (0.42) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |