Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1095320 | 0.80 | LMNA (0.39) | F10MAPK1LMNAKMT2A | |
| SCHEMBL1097360 | 0.75 | MIF (0.54) | F10MAPK1 | |
| SCHEMBL1096582 | 0.71 | HPGD (0.43) | F10MAPK1LMNAKMT2A | |
| SCHEMBL3089643 | 0.70 | HPGD (0.38) | F10MAPK1LMNAKMT2A | |
| SCHEMBL1096809 | 0.68 | LMNA (0.42) | F10MAPK1LMNAKMT2A | |
| SCHEMBL1096001 | 0.68 | F10 (0.42) | F10MAPK1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL1096088 | 0.68 | F10 (0.42) | F10LMNA | |
| SCHEMBL1095930 | 0.68 | HPGD (0.43) | F10MAPK1LMNAKMT2A | |
| SCHEMBL1097619 | 0.68 | F10 (0.53) | F10LMNAKMT2ATP53 | |
| SCHEMBL4951841 | 0.67 | F10 (0.34) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893572-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006002099-A2 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-01-05 | — | — | WO | disclosed |