SCHEMBL4952158

SCHEMBL4952158

Cc1cc2c(cc1C(C)(C)C)-c1cc(C(C)(C)C)c(C)c(=C(c3cccc(C(F)(F)F)c3)c3cccc(C(F)(F)F)c3)c1=C2C1=CC=CC1

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
CES2 O00748 1/20 0.30
ALDH1A1 P00352 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
MAPT P10636 1/20 0.30
ADORA1 P30542 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4949609 0.82
SCHEMBL5083325 0.74
SCHEMBL4949602 0.71
SCHEMBL1481207 0.69
Hydrochloric Acid SCHEMBL5986238 0.67
SCHEMBL14735581 0.67 CES2 (0.31) CES2
Hydrochloric Acid SCHEMBL16531828 0.66 CES2 (0.31) CES2
SCHEMBL14735582 0.66 CES2 (0.34) MEN1KMT2AGAAHTTRAB9A
Hydrochloric Acid SCHEMBL18421716 0.66 TAS1R3 (0.32) MEN1KMT2AGAAHTTRAB9A
Hydrochloric Acid SCHEMBL18421715 0.66 MEN1 (0.31) MEN1KMT2AHTTRAB9ACES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160280819-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE-BASED COPOLYMER, PROPYLENE POLYMER, PROPYLENE-BASED POLYMER COMPOSITION, AND USE OF THOSE MITSUI CHEMICALS, INC. (JP) 2016-09-29 US disclosed
EP-1900758-B9 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2016-07-13 EP disclosed
US-9382356-B2 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. (JP) 2016-07-05 US disclosed
EP-1900758-B1 METHOD FOR PRODUCING OLEFIN POLYMER MITSUI CHEMICALS INC (JP) 2016-03-16 EP disclosed
US-20080220193-A1 Catalyst for olefin polymerization, method for producing olefin polymer, method for producing propylene-based copolymer, propylene polymer, propylene-based polymer composition, and use of those MITSUI CHEMICALS, INC. 2008-09-11 US disclosed
EP-1900758-A1 CATALYST FOR OLEFIN POLYMERIZATION, METHOD FOR PRODUCING OLEFIN POLYMER, METHOD FOR PRODUCING PROPYLENE COPOLYMER, PROPYLENE POLYMER, PROPYLENE POLYMER COMPOSITION, AND USE OF THOSE Mitsui Chemicals, Inc. (JP) 2008-03-19 EP disclosed