Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.44 |
| ▸ | DRD1 | P21728 | 4/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | DRD3 | P35462 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL629136 | 0.91 | KDM1A (0.53) | KDM1APTGS1PTGS2MAOACYP2D6 | |
| SCHEMBL627994 | 0.86 | MAOA (0.58) | KDM1APTGS1PTGS2MAOAADRA2A | |
| SCHEMBL5484265 | 0.75 | LMNA (0.42) | KDM1ADRD3LMNAALDH1A1DRD2 | |
| SCHEMBL30622707 | 0.74 | KDM1A (0.59) | KDM1APTGS1PTGS2MAOACYP2D6 | |
| SCHEMBL18550498 | 0.74 | KDM1A (0.59) | KDM1APTGS1PTGS2MAOACYP2D6 | |
| SCHEMBL7611171 | 0.71 | BCHE (0.56) | KDM1APTGS1PTGS2MAOACYP2D6 | |
| SCHEMBL293951 | 0.70 | KDM1A (0.61) | KDM1APTGS1PTGS2MAOACYP2D6 | |
| SCHEMBL29557425 | 0.70 | KDM1A (0.61) | KDM1APTGS1PTGS2MAOACYP2D6 | |
| SCHEMBL18890496 | 0.69 | KDM1A (0.53) | KDM1ACYP2D6CHRM2HTR1AADRA2A | |
| SCHEMBL29459667 | 0.69 | KDM1A (0.53) | KDM1ACYP2D6CHRM2HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883987-A1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M Innovative Properties Company (US) | 2008-02-06 | — | — | EP | claimed |
| WO-2006124738-A1 | SUBSTITUTED PHENOTHIAZINE REDOX SHUTTLES FOR RECHARGEABLE LITHIUM-ION CELL | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-11-23 | — | — | WO | claimed |